Results 281 to 290 of about 2,596,459 (367)

Identification and characterization of gene 10 transactivated by hepatitis B virus X protein with DNA microarray assay

, 2003
Jun Cheng, Yan Liu, Yuan Hong, Lin Wang, Yanwei Zhong, Jing Dong, Gang Wang   +6 more
openalex   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Laboratory and Clinical Evaluation of DNA Microarray for the Detection of Carbapenemase Genes in Gram-Negative Bacteria from Hospitalized Patients. [PDF]

Biomed Res Int, 2019
Song Y, Dou F, He S, Zhou Y, Liu Q.
europepmc   +1 more source

Faculty Opinions recommendation of Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

, 2008
Daniel E. Weeks
openalex   +2 more sources

Novel MITF targets identified using a two‐step DNA microarray strategy

Pigment Cell & Melanoma Research, 2008
K. Hoek, N. Schlegel, Ossia M. Eichhoff, D. Widmer, C. Praetorius, Steingrímur Einarsson, S. Valgeirsdóttir, K. Bergsteinsdottir, Alexander Schepsky, R. Dummer, E. Steingrímsson   +10 more
semanticscholar   +1 more source

Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics

Environmental and Molecular Mutagenesis, EarlyView.
Abstract As a part of the International Workshop on Genotoxicity Testing (IWGT) in 2022, a workgroup was formed to evaluate the level of validation and regulatory acceptance of transcriptomic biomarkers that identify genotoxic substances. Several such biomarkers have been developed using various molecular techniques and computational approaches. Within
Matthew J. Meier, Florian Caiment, J. Christopher Corton, Roland Frötschl, Yurika Fujita, Danyel Jennen, Roman Mezencev, Carole Yauk   +7 more
wiley   +1 more source

DNA Microarray-Based Screening and  Characterization of Traditional Chinese Medicine. [PDF]

Microarrays (Basel), 2017
Kiyama R.
europepmc   +1 more source

Microarray-Based Identification of Bacteria in Clinical Samples by Solid-Phase PCR Amplification of 23S Ribosomal DNA Sequences

, 2004
Georg Mitterer, Martin Huber, E. Leidinger, Claudia Kirisits, Werner Lubitz, Manfred W. Mueller, Wolfgang M. Schmidt   +6 more
openalex   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source