Results 311 to 320 of about 410,424 (355)

Patient‐derived tumor organoids highlight the potential of precision medicine in managing pancreatic ductal adenocarcinoma

International Journal of Cancer, EarlyView.
What's New? Only about one‐fifth of patients with pancreatic ductal adenocarcinoma (PDAC) qualify for curative treatment approaches employing adjuvant chemotherapy. Tools to predict PDAC response to chemotherapeutic regimens, however, are lacking.
Christine Nitschke, Charline Phan, Yara Souto, Philipp Walter, Mara Goetz, Gediminas Simkus, Jacob Thastrup, Ronald Simon, Jürgen Kupper, Jakob Izbicki, Steven A. Johnsen, Thilo Hackert, Marianne Sinn, Harriet Wikman, Faik G. Uzunoglu, Tabea M. Sturmheit   +15 more
wiley   +1 more source

Prenatal diagnosis and clinical pregnancy outcome of fetuses with conotruncal defects in a Chinese cohort

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aimed to explore genetic etiologies of conotruncal defects (CTDs) in fetuses by analyzing the results of different genetic tests and to assess pregnancy outcomes of fetuses with CTD in a Chinese prenatal cohort. Methods A total of 146 fetuses that underwent invasive prenatal genetic testing for CTD at the prenatal ...
Min Li, Yi Wu, Yiyao Chen, Hui Wang, Weiwei Cheng, Baoying Ye   +5 more
wiley   +1 more source

The DIKW of Transcriptomics in Ecotoxicology: Extracting Information, Knowledge, and Wisdom From Big Data

Environmental Toxicology and Chemistry, EarlyView.
Jessica A. Head, Jessica D. Ewald, Niladri Basu   +2 more
wiley   +1 more source

Bioinformatic Analysis and Molecular Docking Identify Isorhamnetin Is a Candidate Compound in the Treatment of Pulmonary Artery Hypertension. [PDF]

Anatol J Cardiol
Shao C, Xia W, Liu Y.
europepmc   +1 more source

Reliable detection of beta-thalassemia and G6PD mutations by a DNA microarray.

, 2002
Federica Gemignani, Chiara Perra, Stefano Landi, Federico Canzian, Ants Kurg, Neeme Tönisson, Renzo Galanello, Antonio Cao, Andres Metspalu, Giovanni Romeo   +9 more
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DNA-Microarrays

Zeitschrift für Rheumatologie, 2011
Since their development in the 1990s DNA microarrays have advanced to one of the most important technologies for biomedical research. Miniaturization enables up to 1 million different sequence-specific DNA hybridization tests to be performed on an area of less than 2 cm². Depending on the selection of oligonucleotide sequences, which are assembled on a
R, Biesen, T, Häupl
openaire   +2 more sources

ChemInform Abstract: DNA Biosensors and Microarrays

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Sassolas, A., Leca-Bouvier, B.D., Blum, L.J.   +2 more
openaire   +6 more sources

DNA Microarrays

Angewandte Chemie International Edition, 1999
The complete human genes (ca. 100 000) as well as the whole spectrum of biological diversity should soon be able to be analyzed simultaneously by means of DNA microarrays using the fast technical advances that are occurring in this area. The particular strength of array analysis, typically based on the hybridization of nucleic acid probes attached to ...
, Niemeyer, , Blohm
openaire   +2 more sources

Replication of a DNA Microarray

Journal of the American Chemical Society, 2005
A mechanical method for efficient replication of DNA microarrays is described. The approach consists of three steps. First, a master DNA microarray consisting of single-stranded DNA elements is exposed to a solution containing the biotin-functionalized complement of each array element.
Haohao Lin, Li Sun, Richard M. Crooks
openaire   +3 more sources