Results 331 to 340 of about 2,596,459 (367)
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Nephron Physiology, 2005
Until recently, diagnostic and prognostic assessment of diseased tissues in a Pathology laboratory relied on histological and immunohistological studies. DNA microarray technology now allows the simultaneous analysis of up to thousands of different genes in histological or cytological specimens.
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Until recently, diagnostic and prognostic assessment of diseased tissues in a Pathology laboratory relied on histological and immunohistological studies. DNA microarray technology now allows the simultaneous analysis of up to thousands of different genes in histological or cytological specimens.
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Immobilization of DNA on Microarrays
2005Microarrays are new analytical devices that allow the parallel and simultaneous detection of thousands of target compounds. Microarrays, also called DNA chips, are widely used in gene expression, the genotyping of individuals, point mutations, detection of single nucleotide polymorphisms, and short tandem repeats.
Heise, Christian, Bier, Frank Fabian
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2010
The development of microarray technology has revolutionized RNA and deoxyribonucleic acid (DNA) research. In contrast with traditional biological assays, microarrays allow the simultaneous measurement of tens of thousands of messenger RNA (mRNA) transcripts for gene expression or of genomic DNA fragments for copy number variation analysis.
Stuart C, Sealfon, Tearina T, Chu
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The development of microarray technology has revolutionized RNA and deoxyribonucleic acid (DNA) research. In contrast with traditional biological assays, microarrays allow the simultaneous measurement of tens of thousands of messenger RNA (mRNA) transcripts for gene expression or of genomic DNA fragments for copy number variation analysis.
Stuart C, Sealfon, Tearina T, Chu
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Current Opinion in Oncology, 2003
Since the discovery of the first oncogene 26 years ago, a large body of research has convincingly demonstrated that the initiation and progression of cancers involve the accumulation of genetic aberrations in the cell. Many techniques have been developed to identify these genetic abnormalities.
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Since the discovery of the first oncogene 26 years ago, a large body of research has convincingly demonstrated that the initiation and progression of cancers involve the accumulation of genetic aberrations in the cell. Many techniques have been developed to identify these genetic abnormalities.
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Protein Microarrays Printed from DNA Microarrays
2010Protein arrays are miniaturised and highly parallelised formats of interaction-based functional protein assays. Major bottlenecks in protein microarraying are the limited availability and high cost of purified, functional proteins for immobilisation and the limited stability of immobilised proteins in their functional state. In contrast, protein-coding
Oda, Stoevesandt +2 more
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Producing Protein Microarrays from DNA Microarrays
2011The development of protein microarrays makes possible interaction-based protein assays in miniaturised, multiplexed formats. A major requirement determining their uptake and use is the availability and stability of purified, functional proteins for immobilisation.
Oda, Stoevesandt +2 more
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2008
There are many ways to fabricate DNA microarrays. The four main types of arrays are spotted arrays of pre-made DNA probes, in situ synthesis of DNA arrays, random bead arrays and suspension arrays. The different types of array can address different biological assays.
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There are many ways to fabricate DNA microarrays. The four main types of arrays are spotted arrays of pre-made DNA probes, in situ synthesis of DNA arrays, random bead arrays and suspension arrays. The different types of array can address different biological assays.
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2009
The completion of the Human Genome Project and the emergence of high-throughput technologies at the dawn of the new millennium, are rapidly changing the way we approach biological problems. DNA microarrays represent a promising new technological development, widely used for the investigation and identification of genes associated with important ...
Aristotelis Chatziioannou +1 more
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The completion of the Human Genome Project and the emergence of high-throughput technologies at the dawn of the new millennium, are rapidly changing the way we approach biological problems. DNA microarrays represent a promising new technological development, widely used for the investigation and identification of genes associated with important ...
Aristotelis Chatziioannou +1 more
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DNA Microarrays in Clinical Oncology
Journal of Clinical Oncology, 2002ABSTRACT: Aberrant gene expression is critical for tumor initiation and progression. However, we lack a comprehensive understanding of all genes that are aberrantly expressed in human cancer. Recently, DNA microarrays have been used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for ...
Sridhar, Ramaswamy, Todd R, Golub
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