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Electronic Microarrays in DNA Computing
Journal of Nanoscience and Nanotechnology, 2011DNA Computing is a rapidly-developing interdisciplinary area which could benefit from more experimental results to solve practical problems with the current biological tools. In this study, we have integrated microelectronics and molecular biology techniques for the storage of information and basic arithmetic operations via DNA.
Jennifer Reiber Kyle +5 more
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DNA Microarrays in Clinical Oncology [PDF]
Journal of Clinical Oncology, 2002 ABSTRACT: Aberrant gene expression is critical for tumor initiation and progression. However, we lack a comprehensive understanding of all genes that are aberrantly expressed in human cancer. Recently, DNA microarrays have been used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for ...
Sridhar Ramaswamy, Todd R. Golub
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Immobilization of DNA on Microarrays
2005Microarrays are new analytical devices that allow the parallel and simultaneous detection of thousands of target compounds. Microarrays, also called DNA chips, are widely used in gene expression, the genotyping of individuals, point mutations, detection of single nucleotide polymorphisms, and short tandem repeats.
Heise, Christian, Bier, Frank Fabian
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Protein Microarrays Printed from DNA Microarrays
2010Protein arrays are miniaturised and highly parallelised formats of interaction-based functional protein assays. Major bottlenecks in protein microarraying are the limited availability and high cost of purified, functional proteins for immobilisation and the limited stability of immobilised proteins in their functional state. In contrast, protein-coding
Oda Stoevesandt +2 more
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Producing Protein Microarrays from DNA Microarrays
2011The development of protein microarrays makes possible interaction-based protein assays in miniaturised, multiplexed formats. A major requirement determining their uptake and use is the availability and stability of purified, functional proteins for immobilisation.
Oda Stoevesandt +2 more
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Current Genomics, 2003
Recent advances in DNA microarray technology have opened the door for large-scale gene expression screening, functional analysis and genomic profiling. Microarrays offer a new opportunity for genome-wide studies and are quickly revolutionizing biological analyses.
Daniel A. Peiffer +2 more
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Recent advances in DNA microarray technology have opened the door for large-scale gene expression screening, functional analysis and genomic profiling. Microarrays offer a new opportunity for genome-wide studies and are quickly revolutionizing biological analyses.
Daniel A. Peiffer +2 more
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2009
The completion of the Human Genome Project and the emergence of high-throughput technologies at the dawn of the new millennium, are rapidly changing the way we approach biological problems. DNA microarrays represent a promising new technological development, widely used for the investigation and identification of genes associated with important ...
Aristotelis Chatziioannou +1 more
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The completion of the Human Genome Project and the emergence of high-throughput technologies at the dawn of the new millennium, are rapidly changing the way we approach biological problems. DNA microarrays represent a promising new technological development, widely used for the investigation and identification of genes associated with important ...
Aristotelis Chatziioannou +1 more
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An Introduction to DNA Microarrays
2005Oligonucleotide and DNA arrays, or microarrays, have proven to be useful tools to investigate biological function, and are the focal point of an increasing number of studies. However, most papers shed little light on the underlying basis and best use of microarray technology, often leaving a number of important questions unanswered.
Patrick McConnell +2 more
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