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DNA Microarray in Glycobiology
2009DNA microarray analysis enables us to provide a considerable amount of information on glyco-chain expression (Brazma et al. 2001; Ide et al. 2006). DNA microarray experiments are developed to obtain overall transcriptome of cells using DNAs spotted on a slide glass as probes and fluorescently labeled DNAs derived from mRNA samples.
Yasunori Kozutsumi +2 more
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DNA Content Analysis on Microarrays
2004The genome sequencing of protozoan parasites has facilitated the development of powerful postgenomics tools such as DNA microarrays and revolutionized the study of parasite biology. Large-scale genomic comparisons are useful in identifying the extent of genomic variability among related strains and isolates.
Preetam H. Shah +2 more
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Analysis of DNA Microarray Data
Current Topics in Medicinal Chemistry, 2004Recent advances in DNA microarray technology have great impact on many areas of biomedical research and pharmacogenomics: discovering novel targets and genes, elucidating signatures of complex diseases, transcriptional profiling of models for diseases, and the development of individually optimized drugs based on differential gene expression patterns ...
Hubert Hackl +4 more
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DNA Microarray Stochastic Model
IEEE Transactions on Nanobioscience, 2005A stochastic model of the DNA microarray image pixels is presented. The model includes spot pixel intensity distribution, interpixel correlations and the intensity distribution of background noise. The data is indicative of a small exponential additive noise process and a larger Gaussian fluctuation that scales with spot intensity.
S.W. Davies, D.A. Seale
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DNA Microarrays as a Tool in Toxicogenomics
Combinatorial Chemistry & High Throughput Screening, 2004Toxicogenomics is an emerging technology that defines the use of novel genomic techniques to investigate the adverse effects of xenobiotic on gene expression. Toxicogenomics is based on the fact that most of relevant toxicological effects of a compound affect directly or indirectly the gene expression. The most common methods to profile gene expression
Jean-François Remacle +2 more
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Recent developments in DNA microarrays
Current Opinion in Microbiology, 2002DNA microarrays are used to quantify tens of thousands of DNA or RNA sequences in a single assay. Upon their introduction approximately six years ago, DNA microarrays were viewed as a disruptive technology that would fundamentally alter the scientific landscape.
Peter S. Linsley, Daniel D. Shoemaker
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DNA Microarray Technology in Dermatology
Seminars in Cutaneous Medicine and Surgery, 2008In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional groups of genes.
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Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
Science, 1995M. Schena +3 more
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Comparative genomics of BCG vaccines by whole-genome DNA microarray.
Science, 1999M. Behr +6 more
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2008
Although techniques such as RT-PCR and in situ hybridization (ISH) can give information about gene expression, they are limited in scope as typically one gene product is evaluated with each assay. The advent of transcriptional profiling using DNA microarray has revolutionized the field of molecular medicine as measurement of thousands of genes ...
Lyndsay Harris +2 more
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Although techniques such as RT-PCR and in situ hybridization (ISH) can give information about gene expression, they are limited in scope as typically one gene product is evaluated with each assay. The advent of transcriptional profiling using DNA microarray has revolutionized the field of molecular medicine as measurement of thousands of genes ...
Lyndsay Harris +2 more
openaire +2 more sources