Results 231 to 240 of about 299,286 (332)

Genomic characterization of host gene alterations in Theileria annulata-transformed leukocytes. [PDF]

Commun Biol
Dandasena D, Suresh A, Budhwar R, Godwin J, Singh S, Subudhi M, A VM, T A, Roy S, Bhandari V, Sharma P.   +10 more
europepmc   +1 more source

Mutational Analysis of the Drosophila DNA Repair and Recombination Gene mei-9

, 2020
O. Yildiz
openalex   +1 more source

Amplicon DNA Melting Analysis for Mutation Scanning and Genotyping: Cross-Platform Comparison of Instruments and Dyes [PDF]

, 2006
Mark G. Herrmann, Jacob Durtschi, L Kathryn Bromley, Carl T. Wittwer, Karl V. Voelkerding   +4 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes. [PDF]

Nat Commun
Uusküla-Reimand L, Lee CA, Oh RH, Klein ZP, Adler N, Akhtar Alvi S, Langille E, Pasini E, Cheng KCL, Serafimova E, Abd-Rabbo D, Hou H, Tsai R, Bhat M, Schramek D, Wilson MD, Reimand J.   +16 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Somatic Mutation Profiling and Therapeutic Landscape of Breast Cancer in the MENA Region. [PDF]

Cells
Velayutham D, Elango R, Rashid S, Al-Sarraf R, Akhtar M, Ouararhni K, Jithesh PV, Alajez NM.   +7 more
europepmc   +1 more source

Mutational Analysis of the Sequences at the Termini of the Moloney Murine Leukemia Virus DNA Required for Integration

, 1993
John E. Murphy, Teresa de los Santos, Stephen P. Goff   +2 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Whole-exome sequencing for identification of specific gene mutations in an Indian cohort of triple-negative breast cancer patients. [PDF]

Discov Oncol
Preeti P, Das AM, Kumar P, Gogia A, Kumar L, Deo SVS, Mathur S, Janardhanan R, Rawal K, Garg M, Das BC.   +10 more
europepmc   +1 more source