Results 211 to 220 of about 792,120 (349)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Quantitative and spatially resolved detection of multiplexed microRNA from plant tissue via hybridization to hydrogel-bound DNA probes in nanoliter well arrays. [PDF]

Microsyst Nanoeng
Fang J, Doyle PS.
europepmc   +1 more source

Analysis of DNA Single-Locus Probe Data

, 1989
Sirimathie Wewala, Seymour Geisser
openalex   +1 more source

DNA fingerprinting for individual identification and parentage test in Japanese Black cattle using five different mini-and one micro-satellite probes

, 1993
Hideyuki Mannen, Soichi TSUJI
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Probing the Chemistry and Enzymology of Translesion DNA Synthesis: Applications in Developing a Novel “Theranostic” Agent against Leukemia

, 2012
Edward A. Motea
openalex   +1 more source

Probing the structure and in silico stability of cargo loaded DNA icosahedra using MD simulations [PDF]

, 2017
Himanshu Joshi, Dhiraj Bhatia, Yamuna Krishnan, Prabal K. Maiti   +3 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Nanostructure and Corresponding Quenching Efficiency of Fluorescent DNA Probes. [PDF]

Materials (Basel), 2018
Guo W, Wei Y, Dai Z, Chen G, Chu Y, Zhao Y.   +5 more
europepmc   +1 more source

Preclinical Detection of Porcine Circovirus Type 2 Infection Using an Ultrasensitive Nanoparticle DNA Probe-Based PCR Assay

, 2014
Yong Huang, Xiujuan Zhang, Qian Du, Feng‐Yu Wang, Xiaomin Zhao, Wenlong Zhang, Dewen Tong   +6 more
openalex   +2 more sources