Results 211 to 220 of about 3,869,166 (380)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes. [PDF]

Proc Natl Acad Sci U S A, 2020
Marshall JL, Doughty BR, Subramanian V, Guckelberger P, Wang Q, Chen LM, Rodriques SG, Zhang K, Fulco CP, Nasser J, Grinkevich EJ, Noel T, Mangiameli S, Bergman DT, Greka A, Lander ES, Chen F, Engreitz JM.   +17 more
europepmc   +1 more source

First trimester prenatal diagnosis and detection of carriers of haemophilia A using the linked DNA probe DX13. [PDF]

, 1985
R M Winter, Katherine L. Harper, E. Goldman, R.S. Mibashan, R C Warren, Charles H. Rodeck, R. Penketh, R. H. T. Ward, R. M. Hardisty, Marcus Pembrey   +9 more
openalex   +1 more source

Catalytic DNA lead probe [PDF]

Nature Biotechnology, 2001
openaire   +3 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Direct Detection and Discrimination of Nucleotide Polymorphisms Using Anthraquinone Labeled DNA Probes. [PDF]

Front Chem, 2020
Goodchild SA, Gao R, Shenton DP, McIntosh AJS, Brown T, Bartlett PN.   +5 more
europepmc   +1 more source

Biotinylated DNA probes for exotoxin A and pilin genes in the differentiation of Pseudomonas aeruginosa strains [PDF]

, 1988
Mansour Samadpour, S L Moseley, Stephen Lory   +2 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

DNA and RNA editing without sequence limitation using the flap endonuclease 1 guided by hairpin DNA probes. [PDF]

Nucleic Acids Res, 2020
Tian K, Guo Y, Zou B, Wang L, Zhang Y, Qi Z, Zhou J, Wang X, Zhou G, Wei L, Xu S.   +10 more
europepmc   +1 more source

Mycoplasma gallisepticumspecies and strain‐specific recombinant DNA probes [PDF]

, 1989
Mazhar I. Khan, Bruce C. Kirkpatrick, R. Yamamoto   +2 more
openalex   +1 more source