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Probing DNA Structure With Nanoparticles
2005Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures.
Catherine J. Murphy, Rahina Mahtab
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DNA Probes in Diagnostic Pathology
American Journal of Clinical Pathology, 1988Molecular pathology has become firmly established as a distinctive discipline in medicine. It has introduced radical changes in concepts of disease causation and in classification of disease states affecting humans and other organisms. In addition, molecular pathology represents a "new" diagnostic technology with many potentials that have been ...
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Analytical Chemistry, 2013
In this work, a signal amplification supersandwich strategy was developed for highly selective and sensitive detection of cancer cells using aptamer-DNA concatamer-quantum dots (QDs) probes.
Hongying Liu +4 more
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In this work, a signal amplification supersandwich strategy was developed for highly selective and sensitive detection of cancer cells using aptamer-DNA concatamer-quantum dots (QDs) probes.
Hongying Liu +4 more
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1985
The successful diagnosis of a microbial infection is dependent on the ability to confirm the presence of material from pathogenic microorganisms in clinical samples. The diagnostic approaches will vary according to the clinical situation but any test must be able to identify a potential pathogen, or material from that pathogen, amongst complex ...
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The successful diagnosis of a microbial infection is dependent on the ability to confirm the presence of material from pathogenic microorganisms in clinical samples. The diagnostic approaches will vary according to the clinical situation but any test must be able to identify a potential pathogen, or material from that pathogen, amongst complex ...
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DNA Methyltransferase Probing of DNA-Protein Interactions
2006Effective methods of probing chromatin structure without disrupting DNA-protein interactions and associations are necessary for creating an accurate picture of chromatin and its processes in vivo. Expression of cytidine-5 DNA methyltransferases (C5 DMTases) in Saccharomyces cerevisiae provides a powerful noninvasive method of assaying relative DNA ...
Michael P. Kladde, Scott A. Hoose
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Analytical Chemistry, 2010
Quantitative and reproducible data can be obtained from surface-based DNA sensors if variations in the conformation and surface density of immobilized single-stranded DNA capture probes are minimized.
S. M. Schreiner +5 more
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Quantitative and reproducible data can be obtained from surface-based DNA sensors if variations in the conformation and surface density of immobilized single-stranded DNA capture probes are minimized.
S. M. Schreiner +5 more
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Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection.
Science, 2002Multiplexed detection of oligonucleotide targets has been performed with gold nanoparticle probes labeled with oligonucleotides and Raman-active dyes.
Y. Cao, Rongchao Jin, C. Mirkin
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Nanoparticles and DNA Probes Based on DNA‐Fluorophore Conjugates
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
J. Raedler +3 more
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DNA fingerprints of farm animals generated by microsatellite and minisatellite DNA probes.
Animal Genetics, 2009A multi-locus DNA probe, R18.1, derived from a bovine genomic library, detected DNA fingerprints of highly polymorphic loci in hybridization to genomic DNA from poultry and sheep, and of moderate polymorphic loci in cattle and human DNA.
A. Haberfeld +4 more
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Hybridization kinetics of double-stranded DNA probes for rapid molecular analysis.
In Analysis, 2009This study reports the hybridization kinetics of double-stranded DNA probes for rapid molecular analysis. Molecular binding schemes based on double-stranded DNA probes have been developed for quantitative detection of various biomolecules, such as ...
Vinay Gidwani +3 more
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