Results 231 to 240 of about 3,810,652 (392)

Longitudinal assessment of DNA repair signature trajectory in prodromal versus established Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Anwer D, Montaldo NP, Novoa-Del-Toro EM, Domanska D, Nilsen HL, Polster A.   +5 more
europepmc   +1 more source

DNA double-strand break repair-pathway choice in somatic mammalian cells

Nature reviews. Molecular cell biology, 2019
R. Scully, Arvind Panday, Rajula Elango, Nicholas A. Willis   +3 more
semanticscholar   +1 more source

Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System

, 2019
Seung‐Joo Lee, Rou-Jia Sung, Gregory L. Verdine   +2 more
openalex   +1 more source

The Role of DNA Repair in Somatic Hypermutation of Immunoglobulin Genes [PDF]

, 1998
Nayun Kim, Ursula Storb
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

AMPK phosphorylates WIP1 to promote DNA repair and radioresistance in cancer cells. [PDF]

Cell Death Dis
Lu M, Dong X, Wu C, Wang G, Wang H, Pan Y, Qin Y, Song Y, Pan H, Liu S, Zhang K, Zhang X, Qu J, Yang Z.   +13 more
europepmc   +1 more source

NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Proceedings of the National Academy of Sciences of the United States of America, 2018
Yujun Hou, Sofie Lautrup, Stephanie Cordonnier, Yue Wang, D. Croteau, Eduardo Zavala, Yongqing Zhang, Kanako Moritoh, J. O’Connell, Beverly A. Baptiste, T. Stevnsner, M. Mattson, V. Bohr   +12 more
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

DNA repair helicases: from mechanistic understanding to therapeutic implications. [PDF]

NAR Cancer
Menon V, Gueble SE.
europepmc   +1 more source

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.

Annual Review of Biochemistry, 2010
M. Lieber
semanticscholar   +1 more source