Results 341 to 350 of about 3,810,652 (392)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Impact of DNA repair gene variants on male infertility susceptibility in south Indian population

M. Venkateswara Rao, K. V. N. Geetha Devi, D. Rajarajeswari, K. Ashalatha   +3 more
openalex   +2 more sources

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Refined DNA repair manipulation enables a universal knock-in strategy in mouse embryos. [PDF]

Nat Commun
Chen H, Tan Q, Li L, Li L, Fu J, Zhu W, Li J, Wang Y, Li S, Li H, Sun Y, Sun Q, Lu Z, Liu Z.   +13 more
europepmc   +1 more source

Structural switches: intracellular G-quadruplexes modulate DNA repair and genome maintenance in <i>Deinococcus radiodurans</i>. [PDF]

mBio
Tewari H, Mishra S, Kota S.
europepmc   +1 more source

FTO suppresses DNA repair by inhibiting PARP1. [PDF]

Nat Commun
Zhu T, Tan JZA, Zhang L, Huang H, Das SS, Cheng F, Padmanabhan P, Jones MJK, Lee M, Lee A, Widagdo J, Anggono V.   +11 more
europepmc   +1 more source

A novel DNA repair-independent role for Gen nuclease in promoting unscheduled polyploidy cell proliferation. [PDF]

PLoS Genet
Budzyk M, Simon A, Mace AS, Basto R.
europepmc   +1 more source

Upregulation of POLE and proficient DNA repair are features of CIC::DUX4 sarcomas. [PDF]

NPJ Precis Oncol
Seligson ND, Paragji A, Shahalam F, Yilma B, Chen JL.   +4 more
europepmc   +1 more source

Uncovering the Role of DNA Repair Impairment in UVA-Induced Mutagenesis in Human Xeroderma Pigmentosum Variant Cells. [PDF]

Mol Carcinog
Corradi C, Moreno NC, Quintero-Ruiz N, Silva Leandro GD, Teatin Latancia M, de Souza TA, Munford V, Menck CFM.   +7 more
europepmc   +1 more source

The role of the oncoprotein DEK in DNA replication stress and damage repair

, 2013
Anja Deutzmann
openalex   +1 more source