Results 161 to 170 of about 31,191 (185)

Human Geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis

EMBO Journal, 2004
Raffaella Zamponi
exaly   +2 more sources

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The depletion of TRAIP results in the retention of PCNA on chromatin during mitosis, leads to inhibiting DNA replication initiation

bioRxiv
Loading PCNA onto chromatin is a pivotal step in DNA replication, cell cycle progression, and genome integrity. Conversely, unloading PCNA from chromatin is equally crucial for maintaining genome stability.
Y. Shiomi, Akiyo Hayashi, Yuichiro Saito, Masato T. Kanemaki, H. Nishitani   +4 more
semanticscholar   +1 more source

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Proceedings of the National Academy of Sciences of the United States of America, 2021
Ukhyun Jo, Yasuhisa Murai, Liton Kumar Saha   +2 more
exaly  

Stabilisation of half MCM ring by Cdt1 during DNA insertion

Nature Communications, 2021
Jordi Frigola
exaly  

SETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM

Science China Life Sciences
Hongguo Duan, Shuang Wang, Wen-Jie Shu, Yongjia Tong, Hai-Zhen Long, Guohong Li, Hai-Ning Du, Mengyuan Zhao   +7 more
semanticscholar   +1 more source

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin

Nature, 2004
Yunje Cho
exaly  

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

Nature Cell Biology, 2001
Domenico Maiorano, J Julian Blow
exaly  

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

Science, 2000
J. Wohlschlegel, Brian T. Dwyer, S. Dhar, Christin Cvetic, J. Walter, Anindya Dutta   +5 more
semanticscholar   +1 more source

Targeted ubiquitination of CDT1 by the DDB1–CUL4A–ROC1 ligase in response to DNA damage

Nature Cell Biology, 2004
Chad M Mccall, Tomohiko Ohta, Yue Xiong
exaly  

PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication

Nature Cell Biology, 2005
Johannes C Walter
exaly