Results 71 to 80 of about 3,598,749 (292)

Quantum Well Model for Charge Transfer in Aperiodic DNA and Superlattice Sequences

open access: yesBiophysica
This study presents a quantum well model using the transfer matrix technique to analyze the charge transfer characteristics of nanostructure sequences in both DNA and superlattices.
Alan Tai
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Genomics dataset of unidentified disclosed isolates

open access: yesData in Brief, 2016
Analysis of DNA sequences is necessary for higher hierarchical classification of the organisms. It gives clues about the characteristics of organisms and their taxonomic position. This dataset is chosen to find complexities in the unidentified DNA in the
Bhagwan N. Rekadwad
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Identification of Rays through DNA Barcoding: An Application for Ecologists [PDF]

open access: yes, 2012
DNA barcoding potentially offers scientists who are not expert taxonomists a powerful tool to support the accuracy of field studies involving taxa that are diverse and difficult to identify.
Owen O'Shea   +39 more
core   +2 more sources

Contribution to the phylogeny of Microgastrinae (Hymenoptera: Braconidae) based on mitochondrial COI and nuclear 28S rDNA genes, with comments on the identity of Pholetesor circumscriptus (Nees, 1834) [PDF]

open access: yesJournal of Insect Biodiversity and Systematics
Microgastrines are diverse group of endoparasitoid wasps attacking caterpillars (Lepidoptera). Despite their importance in biological control, there is still no consensus concerning the phylogeny relationships among taxa.
Parisa Abdoli   +4 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

ITS-dna-sequences

open access: yes, 2018
Following ITS sequencing, reads were demultiplexed using the 2017.10 release of QIIME2 requiring a barcode match. Because the forward and reverse reads do not overlap for this amplicon, DADA2 was used to trim forward and reverse reads to 200 and 100bp ...
Moczek, Armin P.   +5 more
core   +1 more source

Oligonucleotide-Mediated, PCR-Independent Cloning by Homologous Recombination

open access: yesBioTechniques, 2001
We have developed an oligonucleotide-mediated cloning technique based on homologous recombination in Saccharomyces cerevisiae that allows precise DNA sequences to be transferred independent of restriction enzymes and PCR.
D.J. DeMarini   +6 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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