Results 1 to 10 of about 6,016,549 (343)

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

eLife, 2013
The DNA Polymerase α (Pol α)/primase complex initiates DNA synthesis in eukaryotic replication. In the complex, Pol α and primase cooperate in the production of RNA-DNA oligonucleotides that prime synthesis of new DNA.
Rajika L Perera, Rubben Torella, Sebastian Klinge, Mairi L Kilkenny, Joseph D Maman, Luca Pellegrini   +5 more
doaj   +2 more sources

Automated high-throughput DNA synthesis and assembly [PDF]

Heliyon
DNA synthesis and assembly primarily revolve around the innovation and refinement of tools that facilitate the creation of specific genes and the manipulation of entire genomes.
Yuxin Ma, Zhaoyang Zhang, Bin Jia, Yingjin Yuan   +3 more
doaj   +2 more sources

DNA synthesis technologies to close the gene writing gap

Nature Reviews Chemistry, 2023
Synthetic DNA is of increasing demand across many sectors of research and commercial activities. Engineering biology, therapy, data storage and nanotechnology are set for rapid developments if DNA can be provided at scale and low cost.
Alex Hoose, Richard Vellacott, M. Storch, P. Freemont, M. Ryadnov   +4 more
semanticscholar   +1 more source

Comparative genomic analysis of two ST320 Streptococcus pneumoniae isolates, representing serotypes 19A and 19F

BMC Genomic Data, 2023
Background Streptococcus pneumoniae (pneumococcus) represents an important human pathogen, responsible for respiratory and invasive infections in the community.
Weronika Puzia, Jan Gawor, Robert Gromadka, Anna Skoczyńska, Ewa Sadowy   +4 more
doaj   +1 more source

Antiproliferative Effect of Carrageenans on Epidermoid Carcinoma (A431NS) Cells Through Inhibition of DNA Synthesis and Translationally- Controlled Tumour Protein (TPT1) Gene Expression

ASM Science Journal, 2023
Carrageenans are polysaccharide constituents of red seaweed cell walls used in food and medicine as well as thickening agents and excipients in cosmetics and skincare products.
Haema Thevanayagam, Shar Mariam Mohamed, Wan Loy Chu, Zolkapli Eshak   +3 more
doaj   +1 more source

Highly Resistant Serotype 19A Streptococcus pneumoniae of the GPSC1/CC320 Clone from Invasive Infections in Poland Prior to Antipneumococcal Vaccination of Children

Infectious Diseases and Therapy, 2023
Introduction The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced the number of pneumococcal infections.
Weronika Puzia, Jan Gawor, Robert Gromadka, Karolina Żuchniewicz, Izabela Wróbel-Pawelczyk, Patrycja Ronkiewicz, Agnieszka Gołębiewska, Waleria Hryniewicz, Ewa Sadowy, Anna Skoczyńska   +9 more
doaj   +1 more source

Case Report of COVID-19 after Full Vaccination: Viral Loads and Anti-SARS-CoV-2 Antibodies

Diagnostics, 2021
The introduction of effective vaccines against SARS-CoV-2 is expected to prevent COVID-19. However, sporadic cases of infection in vaccinated persons have been reported. We describe a case of a double-dose vaccinated woman with COVID-19.
Magdalena Komiazyk, Jaroslaw Walory, Jan Gawor, Iza Ksiazek, Robert Gromadka, Anna Baraniak   +5 more
doaj   +1 more source

Cyclocytidine hydrochloride inhibits the synthesis of relaxed circular DNA of hepatitis B virus [PDF]

PeerJ, 2022
Background Cyclocytidine hydrochloride (HCl) has been reported to inhibit DNA synthesis by affecting DNA polymerase. Here, we tested the antiviral effect of cyclocytidine on hepatitis B virus (HBV) DNA synthesis, which is reliant on DNA polymerase ...
Xue Wang, Yihan Xiao, Zhigang Cui, Zongxin Li, Lihua Li, Lixian Wu, Feifei Yin, Xiuji Cui   +7 more
doaj   +2 more sources

Taming the Beast of Biology: Synthetic Biology and Biological Systems Engineering

CHIMIA, 2020
Despite the availability of a variety of ' -omics ' technologies to support the system-wide analysis of industrially relevant microorganisms, the manipulation of strains towards an economically relevant goal remains a challenge.
Sven Panke
doaj   +1 more source

Bacterial Communities Associated with Poa annua Roots in Central European (Poland) and Antarctic Settings (King George Island)

Microorganisms, 2021
Poa annua (annual bluegrass) is one of the most ubiquitous grass species in the world. In isolated regions of maritime Antarctica, it has become an invasive organism threatening native tundra communities.
Anna Znój, Jakub Grzesiak, Jan Gawor, Robert Gromadka, Katarzyna J. Chwedorzewska   +4 more
doaj   +1 more source