Results 181 to 190 of about 6,016,549 (343)

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

Molecular and Cellular Biology, 1994
B. Cheatham, C. Vlahos, L. Cheatham, Lois Wang, J. Blenis, C. Kahn   +5 more
semanticscholar   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Structural basis of error-prone DNA synthesis by DNA polymerase θ. [PDF]

Nat Commun
Li C, Maksoud LM, Gao Y.
europepmc   +1 more source

THE FINE STRUCTURE OF THE GENE CONTROLLING THE SYNTHESIS OF DNA POLYMERASE IN BACTERIOPHAGE T4B [PDF]

, 1969
S. I. Alikhanian, V.Z. Pogosov
openalex   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β. [PDF]

Nat Commun
Weaver TM, Ryan BJ, Thompson SH, Hussen AS, Spencer JJ, Xu Z, Schnicker NJ, Freudenthal BD.   +7 more
europepmc   +1 more source

INDUCTION OF CELLULAR DNA SYNTHESIS BY POLYOMA VIRUS [PDF]

, 1965

openalex   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Replisome loading reduces chromatin motion independent of DNA synthesis. [PDF]

Elife, 2023
Pabba MK, Ritter C, Chagin VO, Meyer J, Celikay K, Stear JH, Loerke D, Kolobynina K, Prorok P, Schmid AK, Leonhardt H, Rohr K, Cardoso MC.   +12 more
europepmc   +1 more source