Results 11 to 20 of about 6,016,549 (343)

Batch Optimization for DNA Synthesis [PDF]

open access: yes2021 IEEE International Symposium on Information Theory (ISIT), 2021
Large pools of synthetic DNA molecules have been recently used to reliably store significant volumes of digital data. While DNA as a storage medium has enormous potential because of its high storage density, its practical use is currently severely limited because of the high cost and low throughput of available DNA synthesis technologies.
Konstantin Makarychev   +3 more
openaire   +3 more sources

DNA Synthesis

open access: yesDefinitions, 2020
DNA Synthesis is the polymeric linkage of deoxyribose moieties (with adenine, guanine, cytosine, or thymine side chains) by phosphate groups attached to their 5-prime and 3-prime sugar hydroxyls.

semanticscholar   +1 more source

A first insight into the genome of Prototheca wickerhamii, a major causative agent of human protothecosis

open access: yesBMC Genomics, 2021
Background Colourless microalgae of the Prototheca genus are the only known plants that have consistently been implicated in a range of clinically relevant opportunistic infections in both animals and humans.
Zofia Bakuła   +7 more
doaj   +1 more source

Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage

open access: yesNature Communications, 2020
New storage technologies are needed to keep up with the global demands of data generation. DNA is an ideal storage medium due to its stability, information density and ease-of-readout with advanced sequencing techniques.
Howon Lee   +6 more
semanticscholar   +1 more source

Translesion DNA Synthesis [PDF]

open access: yesEcoSal Plus, 2012
All living organisms are continually exposed to agents that damage their DNA, which threatens the integrity of their genome. As a consequence, cells are equipped with a plethora of DNA repair enzymes to remove the damaged DNA. Unfortunately, situations nevertheless arise where lesions persist, and these lesions block the progression of the
John P. McDonald   +2 more
openaire   +3 more sources

Assessment of enzymatically synthesized DNA for gene assembly

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Phosphoramidite chemical DNA synthesis technology is utilized for creating de novo ssDNA building blocks and is widely used by commercial vendors. Recent advances in enzymatic DNA synthesis (EDS), including engineered enzymes and reversibly terminated ...
Brooke L. Simmons   +4 more
doaj   +1 more source

DNA-templated synthesis optimization [PDF]

open access: yesNatural Computing, 2017
In chemistry, synthesis is the process in which a target compound is produced in a step-wise manner from given base compounds. A recent, promising approach for carrying out these reactions is DNA-templated synthesis, since, as opposed to more traditional methods, this approach leads to a much higher effective molarity and makes much desired one-pot ...
Bjarke N. Hansen   +3 more
openaire   +6 more sources

The DNA polymerases of Drosophila melanogaster

open access: yesFly, 2020
DNA synthesis during replication or repair is a fundamental cellular process that is catalyzed by a set of evolutionary conserved polymerases.
Steven J. Marygold   +9 more
doaj   +1 more source

The use of apolipoprotein A-I as a component of serum-free nutrient medium for bone marrow cell culture

open access: yesСибирский научный медицинский журнал, 2020
An important step in preparation of cells for cell therapy and tissue engineering is the cultivation of cells in vitro. The aim of this work is to study the effect of human apolipoprotein A-I (apoA-I) on the functional activity of cultured bone marrow ...
A. Yu. Gorodetskaya   +4 more
doaj   +1 more source

An optimized method for high quality DNA extraction from microalga Prototheca wickerhamii for genome sequencing

open access: yesPlant Methods, 2017
Background The complex cell wall structure of algae often precludes efficient extraction of their genetic material. The purpose of this study was to design a next-generation sequencing-suitable DNA isolation method for unicellular, achlorophyllous, yeast-
Tomasz Jagielski   +5 more
doaj   +1 more source

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