Results 221 to 230 of about 1,866,190 (292)
A conserved thumb domain insertion in DNA polymerase epsilon supports processive DNA synthesis. [PDF]
Ahmad S, Zhang S, Meng X.
europepmc +1 more source
Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase [PDF]
Ayumi Yamada +3 more
openalex +1 more source
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
DNA synthesis across DNA hairpins by human PrimPol. [PDF]
Boldinova EO +4 more
europepmc +1 more source
Structural Basis of Ubiquitin Recognition by Translesion Synthesis DNA Polymerase ι
Gaofeng Cui +6 more
openalex +2 more sources
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
SNF2L suppresses nascent DNA gap formation to promote DNA synthesis. [PDF]
Nelligan A, Dungrawala H.
europepmc +1 more source
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti +3 more
wiley +1 more source

