Results 221 to 230 of about 6,016,549 (343)

Aberrant mitochondrial DNA synthesis in macrophages exacerbates inflammation and atherosclerosis. [PDF]

open access: yesNat Commun
Natarajan N   +16 more
europepmc   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

open access: yesAdvanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang   +9 more
wiley   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Catalytic and noncatalytic functions of DNA polymerase κ in translesion DNA synthesis. [PDF]

open access: yesNat Struct Mol Biol
Sellés-Baiget S   +17 more
europepmc   +1 more source

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