Results 261 to 270 of about 6,016,549 (343)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis. [PDF]

open access: yesNat Commun
Salas-Lloret D   +11 more
europepmc   +1 more source

Side‐Chains Engineered Self‐Assembly of Ortho‐Benzodipyrrole‐Based Acceptors: Comprehensive Exploration of Structure‐Interface‐Photovoltaics Correlations

open access: yesAdvanced Functional Materials, EarlyView.
The side‐chain configuration in the bay region of C‐shaped ortho‐benzodipyrrole‐based non‐fullerene acceptors plays a crucial role in their self‐assembly, single‐crystal structures, and optoelectronic properties. The closely correlated molecular structure and performance underscore the importance of minimizing A–A self‐aggregation and enhancing D–A ...
Yung‐Jing Xue   +18 more
wiley   +1 more source

Myxococcus xanthus translesion DNA synthesis protein ImuA is an ATPase enhanced by DNA. [PDF]

open access: yesProtein Sci
Lichimo K   +7 more
europepmc   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

open access: yesAdvanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri   +4 more
wiley   +1 more source

Asymmetric RNA synthesis in vitro: heterologous DNA-enzyme systems; E. coli RNA polymerase.

open access: green, 1965
A.J.E. Colvill   +4 more
openalex   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

RAD18 O-GlcNAcylation promotes translesion DNA synthesis and homologous recombination repair. [PDF]

open access: yesCell Death Dis
Ma X   +13 more
europepmc   +1 more source

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