AMINO ACID DEPENDENT CONTROL OF DNA SYNTHESIS IN BACTERIA AND VEGETATIVE PHAGE
E. Kellenberger, Karl G. Lark, A. Bolle
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Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
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BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis. [PDF]
Salas-Lloret D+11 more
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The side‐chain configuration in the bay region of C‐shaped ortho‐benzodipyrrole‐based non‐fullerene acceptors plays a crucial role in their self‐assembly, single‐crystal structures, and optoelectronic properties. The closely correlated molecular structure and performance underscore the importance of minimizing A–A self‐aggregation and enhancing D–A ...
Yung‐Jing Xue+18 more
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Myxococcus xanthus translesion DNA synthesis protein ImuA is an ATPase enhanced by DNA. [PDF]
Lichimo K+7 more
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Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri+4 more
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Ni(II) Cylinders Damage DNA in Cancer Cells and Preferentially Bind Y-Shaped DNA Three-Way Junctions Blocking DNA Synthesis. [PDF]
Malina J, Kostrhunova H, Brabec V.
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Asymmetric RNA synthesis in vitro: heterologous DNA-enzyme systems; E. coli RNA polymerase.
A.J.E. Colvill+4 more
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Metal Nanoclusters for Cancer Imaging and Treatment
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu+5 more
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RAD18 O-GlcNAcylation promotes translesion DNA synthesis and homologous recombination repair. [PDF]
Ma X+13 more
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