Results 21 to 30 of about 1,866,190 (292)

Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis. [PDF]

open access: yesPLoS Pathogens, 2010
Modulation of host DNA synthesis is essential for many viruses to establish productive infections and contributes to viral diseases. Human cytomegalovirus (HCMV), a large DNA virus, blocks host DNA synthesis and deregulates cell cycle progression.
Zhikang Qian   +4 more
doaj   +1 more source

DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae [PDF]

open access: yes, 1995
The ability of yeast DNA polymerase mutant strains to carry out repair synthesis after UV irradiation was studied by analysis of postirradiation molecular weight changes in cellular DNA.
Budd, Martin E., Campbell, Judith L.
core   +2 more sources

Nostoc edaphicum CCNP1411 from the Baltic Sea—A New Producer of Nostocyclopeptides

open access: yesMarine Drugs, 2020
Nostocyclopeptides (Ncps) constitute a small class of nonribosomal peptides, exclusively produced by cyanobacteria of the genus Nostoc. The peptides inhibit the organic anion transporters, OATP1B3 and OATP1B1, and prevent the transport of the toxic ...
Anna Fidor   +5 more
doaj   +1 more source

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells [PDF]

open access: yes, 2010
Nucleotide excision repair (NER) is the most versatile DNA repair system that deals with the major UV photoproducts in DNA, as well as many other DNA adducts.
Cloney, Ross   +13 more
core   +3 more sources

Studies on the relation between heme and nucleic acid syntheses in erythroid cell. II. Nucleic acid synthesis in erythroblast of anemic rat treated with aminopterin and bromouracil [PDF]

open access: yes, 1968
With the bone marrow of anemic rats, which had received the repeated injections of phenylhydrazine once a day for three to four days, the effects of aminopterin and bromouracil on the nucleic acid metabolism of erythroblasts were observed in vivo ...
Shigehisa, Morio
core   +1 more source

The cell cycle–apoptosis connection revisited in the adult brain [PDF]

open access: yes, 2005
Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
core   +3 more sources

High‐throughput sequencing approach in analysis of microbial communities colonizing natural gas pipelines

open access: yesMicrobiologyOpen, 2019
This study provides a deep modern insight into the phylogenetic diversity among bacterial consortia found in working and nonworking high‐methane natural gas pipelines located in Poland.
Agnieszka Staniszewska   +6 more
doaj   +1 more source

Structure and mechanism of human DNA polymerase η [PDF]

open access: yes, 2010
The variant form of the human syndrome xeroderma pigmentosum (XPV) is caused by a deficiency in DNA polymerase eta (Pol eta), a DNA polymerase that enables replication through ultraviolet-induced pyrimidine dimers.
A Alt   +66 more
core   +2 more sources

Morphologic and Cellular Changes Induced by Selective Laser Trabeculoplasty

open access: yesClinical Ophthalmology, 2022
Meenakashi Gupta,1 Jae Young Heo,2 Haiyan Gong,3 Elliot Cha,3 Mark Latina,4,5 Douglas J Rhee2 1Department of Ophthalmology, New York Eye & Ear Infirmary of Mt.
Gupta M   +5 more
doaj  

The Ability of Lytic Staphylococcal Podovirus vB_SauP_phiAGO1.3 to Coexist in Equilibrium With Its Host Facilitates the Selection of Host Mutants of Attenuated Virulence but Does Not Preclude the Phage Antistaphylococcal Activity in a Nematode Infection Model

open access: yesFrontiers in Microbiology, 2019
Phage vB_SauP_phiAGO1.3 (phiAGO1.3) is a polyvalent Staphylococcus lytic podovirus with a 17.6-kb genome (Gozdek et al., 2018). It can infect most of the Staphylococcus aureus human isolates of dominant clonal complexes.
Aleksandra Głowacka-Rutkowska   +9 more
doaj   +1 more source

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