Results 301 to 310 of about 6,016,549 (343)
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DNA and RNA Synthesis: Antifolates
ChemInform, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Rudolf L. Then +2 more
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Differential effects of heparin on replicative DNA synthesis and unscheduled DNA synthesis
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1977The effect of heparin on DNA synthesis was compared between replicative DNA synthesis and unscheduled DNA synthesis. Replicative DNA synthesis in permeable cells or nuclei prepared from rapidly growing mouse ascites sarcoma cells was inhibited by heparin.
Seki, S, Oda, T
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DNA synthesis in human lymphocytes: Intermediates in DNA synthesis, in vitro and in vivo
Journal of Molecular Biology, 1975Two in vitro systems, one using a whole cell lysate, and the other a suspension of washed nuclei prepared from a human lymphocyte line, are characterized with respect to their requirements for the synthesis of DNA and to the nature of the synthetic product.
M. Goulian, B.Y. Tseng
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DNA Synthesis and Genotoxicity
Digestion, 1990In a recent report, Burlinson et al. [Carcinogenesis 1989;10:1425-1428] published the results of an experiment which they claim shows that omeprazole induces unscheduled DNA synthesis (UDS) in rat gastric mucosa (i.e. DNA repair). The Burlinson method measures the incorporation of tritiated thymidine into cells undergoing DNA synthesis.
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Informational DNA Synthesis Distinguished from That of Nuclear DNA by Inhibitors of DNA Synthesis
Science, 1971With inhibitors of DNA synthesis used in the presence of ethidium bromide, it has been possible to distinguish between synthesis of informational DNA (I-DNA) and that of nuclear DNA. Hydroxyurea depresses I-DNA synthesis preferentially but does not affect DNA transport between cell compartments.
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DNA — Structure and Enzymatic Synthesis
New England Journal of Medicine, 1967IN the past ten years there has been a phenomenal increase in knowledge of the mechanism of synthesis of deoxyribonucleic acid (DNA) in bacterial, mammalian and virus–infected cell systems. The introduction of new technics and instrumentation has led to further eludication of DNA structure and physical properties, and essentially complete confirmation ...
Morton N. Swartz, Gerald Medoff
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Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase.
Biochemistry, 1988We have determined the fidelity of in vitro DNA synthesis catalyzed at high temperature by the DNA polymerase from the thermophilic bacterium Thermus aquaticus.
Kenneth R. Tindall, T. Kunkel
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Synthesis of DNA with Phenanthridinium as an Artificial DNA Base
The Journal of Organic Chemistry, 2004A phenanthridinium-containing DNA building block was synthesized as an ethidium nucleoside analogue starting from 3,8-diamino-6-phenyl-phenanthridine. Using this building block, oligonucleotides bearing the phenanthridinium moiety as an artificial DNA base were prepared via automated solid-phase phosphoramidite chemistry.
Huber, R., Amann, N., Wagenknecht, H.-A.
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Synthesis and DNA Binding Properties of DNA-PNA Chimeras
Nucleosides, Nucleotides and Nucleic Acids, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
BARONE, GUIDO +8 more
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Inhibitors of DNA Synthesis [PDF]
, 1974 The mechanism of DNA replication in prokaryotic and even more in eukaryotic cells is a complex process in which apparently more than one DNA polymerizing enzyme system is involved.
Walter Kersten, Helga Kersten
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