Results 31 to 40 of about 6,016,549 (343)
Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology.
Cold Spring Harbor Perspectives in Biology, 2017 The chemical synthesis of DNA oligonucleotides and their assembly into synthons, genes, circuits, and even entire genomes by gene synthesis methods has become an enabling technology for modern molecular biology and enables the design, build, test, learn,
R. Hughes, A. Ellington
semanticscholar +1 more source
Enzymatic synthesis of perfluoroalkylated DNA [PDF]
Bioorganic & Medicinal Chemistry, 2009 Thymidine analogues 5-trifluoromethyl-, 5-pentafluoroethyl- and 5-(heptafluoro-n-propyl)-2'-deoxyuridines were synthesised and converted into the corresponding 5'-triphosphates 1a-c. Performing DNA polymerase-catalyzed primer extension reactions these modified nucleotides were incorporated into DNA to create perfluoroalkylated nucleic acids.
Holzberger, Bastian, Marx, Andreas
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Morphologic and Cellular Changes Induced by Selective Laser Trabeculoplasty
Clinical Ophthalmology, 2022 Meenakashi Gupta,1 Jae Young Heo,2 Haiyan Gong,3 Elliot Cha,3 Mark Latina,4,5 Douglas J Rhee2 1Department of Ophthalmology, New York Eye & Ear Infirmary of Mt.
Gupta M +5 more
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Frontiers in Microbiology, 2019 Phage vB_SauP_phiAGO1.3 (phiAGO1.3) is a polyvalent Staphylococcus lytic podovirus with a 17.6-kb genome (Gozdek et al., 2018). It can infect most of the Staphylococcus aureus human isolates of dominant clonal complexes.
Aleksandra Głowacka-Rutkowska +9 more
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DNA display III. Solid-phase organic synthesis on unprotected DNA. [PDF]
PLoS Biology, 2004 DNA-directed synthesis represents a powerful new tool for molecular discovery. Its ultimate utility, however, hinges upon the diversity of chemical reactions that can be executed in the presence of unprotected DNA.
David R Halpin +3 more
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Synthesis of chemically modified DNA [PDF]
Biochemical Society Transactions, 2016 Naturally occurring DNA is encoded by the four nucleobases adenine, cytosine, guanine and thymine. Yet minor chemical modifications to these bases, such as methylation, can significantly alter DNA function, and more drastic changes, such as replacement with unnatural base pairs, could expand its function.
Shivalingam, A, Brown, T
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New Methods for Synthesizing DNA, RNA, and Phosphonates
CHIMIA, 2005 The development of new methods for the synthesis of DNA, RNA, and phosphonates has enabled new applications in biochemistry and biology.
Marvin H. Caruthers
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A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Eukaryotic family A DNA polymerases are involved in mitochondrial DNA replication or translesion DNA synthesis. Here, we present evidence that the sole family A DNA polymerase from the parasite protozoan E.
Guillermo Pastor-Palacios +2 more
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Enzymatic synthesis of DNA, XXIV. Synthesis of infectious phage phi-X174 DNA. [PDF]
Proceedings of the National Academy of Sciences, 1967 Past attempts at in vitro replication of transforming factor present in DNA have given negative or inconclusive results.(1-3) Rigid proof was lacking that template material had been excluded from the synthetic product. Even if a rigorous demonstration of net synthesis of transforming factor for a given genetic marker were forthcoming, it would still ...
Goulian, Mehran +2 more
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Frontiers in Bioengineering and Biotechnology, 2021 Over the past decades, remarkable progress on phosphoramidite chemistry-based large-scale de novo oligonucleotide synthesis has been achieved, enabling numerous novel and exciting applications.
Li-Fu Song +8 more
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