ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Dynamic machine learning approach for workload prediction in cloud environments. [PDF]
Nashaat M, Moussa W, Rizk R, Saber W.
europepmc +1 more source
A Novel Blockchain-Based Healthcare System Design and Performance Benchmarking on a Multi-Hosted Testbed. [PDF]
Pradhan NR +8 more
europepmc +1 more source
Security in Docker Swarm: orchestration service for distributed software systems
With a constantly increasingly number of services in modern software systems (SOA and micro services), managing such service infrastructure becomes a challenge. Docker Swarm is a popular service orchestration solution that addressed this issue. This makes it a target for attacks, as the orchestrator is entrusted with critical information for a system ...
openaire +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
WiNGS-API: a federated genome/phenome data sharing platform enabling gene discovery and variant classification for rare diseases. [PDF]
Sattanathan N +4 more
europepmc +1 more source
A Blockchain Protocol for Real-Time Application Migration on the Edge. [PDF]
Tošić A +3 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
CLOUD DATA SECURITY METHODS: KUBERNETES VS DOCKER SWARM
openaire +1 more source
Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran +13 more
wiley +1 more source

