Results 161 to 170 of about 138,378 (261)

A Survey of Current Operations-Ready Thermospheric Density Models for Drag Modeling in LEO Operations. [PDF]

J Astronaut Sci
Mutschler S, Pilinski M, Bruinsma S, Sutton E, Tobiska WK, Knipp D, Fang TW, Casali S, Mallik V, DiLorenzo B, Siemes C.   +10 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Understanding Application Containerization with Docker and Docker Swarm

International Journal of Science and Research (IJSR)
openaire   +1 more source

CGeNArateWeb: a web server for the atomistic study of the structure and dynamics of chromatin fibers. [PDF]

Nucleic Acids Res
Farré-Gil D, Bayarri G, Laughton CA, Hospital A, Orozco M.   +4 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

An open-source application for self-service, Health Insurance and Portability Accountability Act-compliant geocoding. [PDF]

J Clin Transl Sci
Gill H, Power K, Jackson C, Johnson J, Llewelyn M, Vallambhatla K, Kane N, Thompson J, Anuforo K, Brokamp C, Hoffman M.   +10 more
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

A multi-source heterogeneous massive operation and maintenance data collection method for substations based on cloud-edge collaboration and artificial intelligence. [PDF]

Sci Rep
Wang J, Zhou Y, Liu N.
europepmc   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Genomics to Notebook (g2nb): Extending the Electronic Notebook to Address the Challenges of Bioinformatics Analysis. [PDF]

J Bioinform Syst Biol
Reich M, Tabor T, Liefeld T, Joshi J, Kim F, Huang E, Thorvaldsdottir H, Blankenberg D, Mesirov JP.   +8 more
europepmc   +1 more source