Results 31 to 40 of about 138,378 (261)
A Comprehensive Feature Comparison Study of Open-Source Container Orchestration Frameworks
Applied Sciences, 2019 (1) Background: Container orchestration frameworks provide support for management ofcomplex distributed applications. Different frameworks have emerged only recently, and they havebeen in constant evolution as new features are being introduced.
Eddy Truyen +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Optimization of Application Deployment Architecture in Container Orchestration
Journal of Applied Informatics and ComputingContainer orchestration has become a widely adopted standard for application deployment among medium to large-scale organizations. Docker Swarm is one of the popular container orchestration tools due to its relatively simple configuration.
Mochamad Rizal Fachrudin +1 more
doaj +1 more source
Swarm Inteligence in Virtual Environment
Journal of Advanced Engineering and Computation, 2019 To simulate some behavior of swarms, the malware was selected as a carrier of intelligence. This article describes the current solution which is fully virtual.
Lukas Revay, Ivan Zelinka
doaj +1 more source
IMPLEMENTASI DOCKER SWARM SEBAGAI HIGH AVAILABILITY HOSTING
, 2022 Pada era modern ini website mempunyai peranan yang sangat penting bagi sebuah perusahaan. Informasi profil institusi, kegiatan perkantoran, bahkan proses jual beli kini dapat dilakukan melalui sebuah website. Kebutuhan akses daring yang semakin tinggi,
NUGROHO, GHOFAR - 185411141
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2014 Project Specification CERN is establishing a large scale private cloud based on OpenStack as part of the expansion of the computing infrastructure for storing the data coming out of the Large Hadron Collider (LHC) experiments.
Agarwal, Nitin, Moreira, Belmiro
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source