Results 231 to 240 of about 511,020 (304)

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Genome-guided discovery and computational prioritization of next generation drug development from <i>Streptomyces</i> sp. VITGV156 (MCC 4965). [PDF]

Front Microbiol
Pattapulavar V, Shah M, Bell I PJ, Ramanujam S, Subburaj S, Arumugam S, Muniyan R, Christopher JG.   +7 more
europepmc   +1 more source

LLM‐Based Scientific Assistants for Knowledge Extraction: Which Design Choices Matter?

Advanced Intelligent Discovery, EarlyView.
A comprehensive framework for optimizing Large Language Models in domain‐specific applications is introduced. The LLM Playground integrates Prompt Engineering, knowledge augmentation, and advanced reasoning strategies to enable systematic comparison of architectures and base models.
David Exler, Manuel Raimann, Marc Münker, Maxim Rosin, Joaquin E. Urrutia Gómez, Christof M. Niemeyer, Markus Reischl, Luca Rettenberger   +7 more
wiley   +1 more source

In Silico Analysis of Potential Stabilizer Binding Sites at Protein-RNA Interfaces. [PDF]

Comput Struct Biotechnol J
Vollmers L, Chen SY, Zacharias M.
europepmc   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Transformation of 3-(4-methoxybenzylidine)-5-(<i>p</i>-tolyl)-2(3<i>H</i>)-furanone into new nitrogen heterocyclic candidates as insecticidal agents with <i>in silico</i> studies. [PDF]

RSC Adv
Gad NM, Haneen DSA, Kamal M, Hosni EM, Hekal MH, Abdalha AA, Abou-Elmagd WSI, Ramadan SK.   +7 more
europepmc   +1 more source

High‐Speed Altitude Regulation With Neuromorphic Camera and Lightweight Embedded Computation

Advanced Intelligent Systems, EarlyView.
Neuromorphic cameras deliver rapid, high‐dynamic‐range sensing but overwhelm embedded processors at high speeds. This work presents a lightweight, optimized Lucas–Kanade optical flow method with parallelization, gyroscopic derotation, and adaptive event slicing.
Simon L. Jeger, Alessandro Marchei, Charbel Toumieh, Dario Floreano   +3 more
wiley   +1 more source

Dysregulated host miRNAs with antiviral potential against SARS-CoV-2 identified from COVID-19 patients. [PDF]

J Transl Med
Ahmad W, Gull B, Baby J, Panicker NG, Khader TA, Rizvi TA, Mustafa F.   +6 more
europepmc   +1 more source

Modular Electronic Microrobots With Onboard Sensor‐Program‐Steered Locomotion

Advanced Intelligent Systems, EarlyView.
Modular electronic smartlet microrobots integrate ambient‐light energy harvesting, photodetection, programmable CMOS control, and bubble‐based actuation within a sub‐millimeter fold‐up architecture. A 58‐bit on‐board CMOS chiplet enables sensor–program steered switching between independently addressable actuators, achieving closed‐loop 2D navigation in
Vineeth K. Bandari, Yeji Lee, Pranathi Adluri, Daniil Karnaushenko, Dmitriy D. Karnaushenko, John S. McCaskill, Oliver G. Schmidt   +6 more
wiley   +1 more source

Wash-Free Multi-Target Super-Resolution Microscopy With Photocaged DNA Labels. [PDF]

Angew Chem Int Ed Engl
Kaltenschnee N, Dietz MS, Kessler LF, Li Y, Kaufmann J, Heckel A, Heilemann M.   +6 more
europepmc   +1 more source