Results 31 to 40 of about 511,020 (304)

An investigation into the effects of commencing haemodialysis in the critically ill [PDF]

, 2012
<b>Introduction:</b> We have aimed to describe haemodynamic changes when haemodialysis is instituted in the critically ill. 3 hypotheses are tested: 1)The initial session is associated with cardiovascular instability, 2)The initial ...
Docking, R., Kinsella, J., Moss, L., Sim, M., Sleeman, D.   +4 more
core   +2 more sources

Potential of Epidermal Growth Factor-like Peptide from the Sea Cucumber Stichopus horrens to Increase the Growth of Human Cells: In Silico Molecular Docking Approach

Marine Drugs, 2022
The sea cucumber is prominent as a traditional remedy among Asians for wound healing due to its high capacity for regeneration after expulsion of its internal organs.
Nur Shazwani Mohd Pilus, Azira Muhamad, Muhammad Ashraf Shahidan, Nurul Yuziana Mohd Yusof   +3 more
doaj   +1 more source

Investigation in haemodynamic stability during intermittent haemodialysis in the critically ill [PDF]

, 2012
No abstract ...
Docking, R., Kinsella, J., Moss, L., Sim, M., Sleeman, D.   +4 more
core   +2 more sources

Research on the Motion and Dynamic Characteristics of the Hose-and-Drogue System under Bow Wave

Aerospace, 2023
To study the hose-and-drogue system’s motion under bow waves, this paper established a dynamic model of the hose-and-drogue system based on the multibody dynamics theory and the rigid ball-and-rod model.
Chunjie Zheng, Haitao Wang, Lanxiang Hu, Yuanli Cai   +3 more
doaj   +1 more source

Design, Synthesis, and Pharmacological Evaluation of Novel Quinolone Aryl Sulfonamide Derivatives as Potent GPR55 Antagonists

Proceedings, 2019
Docking studies of identified GPR55 ligands using a GPR55 inactive state model allow rationalizing key structural features involved in ligand–receptor binding.
Paula Morales, Laura Figuerola-Asencio, Dow H. Hurst, Pingwei Zhao, Mary E. Abood, Patricia H. Reggio, Nadine Jagerovic   +6 more
doaj   +1 more source

Characterization of Monoclonal Antibody–Protein Antigen Complexes Using Small-Angle Scattering and Molecular Modeling

Antibodies, 2017
The determination of monoclonal antibody interactions with protein antigens in solution can lead to important insights guiding physical characterization and molecular engineering of therapeutic targets.
Maria Monica Castellanos, James A. Snyder, Melody Lee, Srinivas Chakravarthy, Nicholas J. Clark, Arnold McAuley, Joseph E. Curtis   +6 more
doaj   +1 more source

DockPro: A VR-Based Tool for Protein-Protein Docking Problem [PDF]

, 2008
Proteins are large molecules that are vital for all living organisms and they are essential components of many industrial products. The process of binding a protein to another is called protein-protein docking.
Balcısoy, Selim, Balcisoy, Selim, Cakici, Serdar, Sezerman, Ugur, Sezerman, Uğur, Sumengen, Selcuk, Sümengen, Selçuk, Çakıcı, Serdar   +7 more
core   +2 more sources

Syzygium aromaticum Extracts as a Potential Antibacterial Inhibitors against Clinical Isolates of Acinetobacter baumannii: An In-Silico-Supported In-Vitro Study

Antibiotics, 2021
Imipenem is the most efficient antibiotic against Acinetobacter baumannii infection, but new research has shown that the organism has also developed resistance to this agent. A.
Abdelhamed Mahmoud, Magdy M. Afifi, Fareed El Shenawy, Wesam Salem, Basem H. Elesawy   +4 more
doaj   +1 more source

Synthesis, Enantiomeric Resolution and Biological Evaluation of HIV Capsid Inhibition Activity for Racemic, (S)- and (R)-PF74

Molecules, 2021
PF74 is a capsid-targeting inhibitor of HIV replication that effectively perturbs the highly sensitive viral uncoating process. A lack of information regarding the optical purity (enantiomeric excess) of the single stereogenic centre of PF74 has resulted
Stuart Ruddell, Elena Sugrue, Sarah Memarzadeh, Lorna Mae Hellam, Sam J. Wilson, David J. France   +5 more
doaj   +1 more source

Highly Flexible Protein-Peptide Docking Using CABS-Dock [PDF]

, 2017
Protein-peptide molecular docking is a difficult modeling problem. It is even more challenging when significant conformational changes that may occur during the binding process need to be predicted. In this chapter, we demonstrate the capabilities and features of the CABS-dock server for flexible protein-peptide docking.
Ciemny, Maciej Pawel, Kurcinski, Mateusz, Kozak, Konrad Jakub, Kolinski, Andrzej, Kmiecik, Sebastian   +4 more
openaire   +3 more sources