Results 51 to 60 of about 157,995 (248)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The impact of doctor-patient communication on patient satisfaction in outpatient settings: implications for medical training and practice

BMC Medical Education
Poor doctor-patient communication significantly contributes to patient dissatisfaction. This study investigates the impact of doctor-patient communication quality on patient satisfaction to guide medical education, clinical training, and hospital ...
Xinyi Chen, Chang Liu, Pengpeng Yan, Hanle Wang, Jingjie Xu, Ke Yao   +5 more
doaj   +1 more source

Doctor-patient relationships through the prism of consumer preferences of chronic patients

Семиотические исследования
In modern social research on medicine, the issue of doctor-patient relationships holds a special place. This publication examines this topic from the perspective of the consumer preferences of patients with chronic diseases. A series of studies served as
Irina E. Finkelstein
doaj   +1 more source

The Mediating Effects of Stigma on Depressive Symptoms in Patients With Tuberculosis: A Structural Equation Modeling Approach

Frontiers in Psychiatry, 2018
Objectives: To date, the complex interrelationships between family function, doctor-patient communication, knowledge about tuberculosis (TB), stigma, and depressive symptoms among patients with TB are insufficiently understood.
Lei Qiu, Lei Qiu, Qin Yang, Yeqing Tong, Zuxun Lu, Yanhong Gong, Xiaoxv Yin   +6 more
doaj   +1 more source

Is there a correlation between the patient-doctor relationship questionnaire and other patient-reported experience measures? [PDF]

, 2020
Patient reported experience measures (PREMs) can quantify the quality of the patient-clinician relationship, which is associated with adherence and improved health.
Joost T.P. Kortlever, Rijk, Léon, Reichel, Lee M., Gonzalez, Amanda I., Léon Rijk, Laura E. Brown, Ring, David, Amanda I. Gonzalez, Lee M. Reichel, David Ring, Kortlever, Joost T.P., Brown, Laura E.   +11 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Nationwide survey of patients’ and doctors’ perceptions of what is needed in doctor - patient communication in a Southeast Asian context

BMC Health Services Research, 2020
Background Asian countries are making efforts to apply the partnership model in doctor-patient communication that has been used effectively in Western countries.
Trung Quang Tran, A. J. J. A. Scherpbier, Jan van Dalen, Dung Do Van, Elaine Pamela Wright   +4 more
doaj   +1 more source

Doctor-Patient communication among Interns at a tertiary care medical college and hospital in eastern India [PDF]

Al Ameen Journal of Medical Sciences, 2021
Background: There is supreme importance for teaching-learning among Interns regarding their perception on Doctor-Patient relationship based on Doctor-Patient communication.
Dharmendra Kumar, Tanay Sinha, Swapan Kumar Paul, Piyali Dutta Chowdhury, Ranabir Pal   +4 more
doaj