Results 51 to 60 of about 166,973,685 (275)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Comparison Study on Teachers’ and Parents’ Assessment of Public Participation in Basic Educational Programs Development

open access: yesПсихологическая наука и образование, 2017
Psychological Science and Education 2016. Vol. 21, no. 4, 19–31 doi:10.17759/pse.2016210403 ISSN: 1814-2052 / 2311-7273 (online) Comparison Study on Teachers’ and Parents’ Assessment of Public Participation in Basic Educational Programs Development
Vachkov I.V.,   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Development of higher education in the regions of Russia: pedagogical staff number

open access: yesPraxis & Saber, 2022
This research aimed to assess the indicators that characterize the number of teaching staff at universities and other higher education institutions (HEIs) in the regions of Russia.
Iuliia Pinkovetskaia
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Special education administration : perceptions of current practice [PDF]

open access: yes, 2004
vii, 82 leaves ; 29 cm. --The Alberta government has indicated that inclusion of special needs students is the preferred placement for children with disabilities.
Olson, Sheelagh   +1 more
core  

Training Pathways and Challenges in Cultivating Outstanding Innovative Talents in Clinical Medicine in China

open access: yesYixue yu zhexue
Currently, there are main models for cultivating top innovative talents in clinical medicine in China. The "5+3+X" program aligns with the standardized physician training system, ensuring a seamless transition from academic education to professional ...
Youhui LUO, Xiaomeng LIU, Jianlin HOU
doaj   +1 more source

W kwestii wyższego stopnia naukowego doktora w Polsce Ludowej

open access: yesStudia Prawa Publicznego, 2019
A higher academic degree that could be earned in the Polish People’s Republic was that of a doctor of a given branch of science (until 1951) or a doctor of science (1951–1958).
Krystyna Wojtczak
doaj   +1 more source

Relationship between Demographic Characteristics and Ethical Reasoning of Nurses Working in Medical Wards [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Professional ethics and moral reasoning are among the critical factors influencing professional nursing practice, the quality of patient care, and the patient’s health outcome.
Firouzeh Safavi   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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