Results 51 to 60 of about 126,831 (267)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Training Pathways and Challenges in Cultivating Outstanding Innovative Talents in Clinical Medicine in China

open access: yesYixue yu zhexue
Currently, there are main models for cultivating top innovative talents in clinical medicine in China. The "5+3+X" program aligns with the standardized physician training system, ensuring a seamless transition from academic education to professional ...
Youhui LUO, Xiaomeng LIU, Jianlin HOU
doaj   +1 more source

W kwestii wyższego stopnia naukowego doktora w Polsce Ludowej

open access: yesStudia Prawa Publicznego, 2019
A higher academic degree that could be earned in the Polish People’s Republic was that of a doctor of a given branch of science (until 1951) or a doctor of science (1951–1958).
Krystyna Wojtczak
doaj   +1 more source

Relationship between Demographic Characteristics and Ethical Reasoning of Nurses Working in Medical Wards [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Professional ethics and moral reasoning are among the critical factors influencing professional nursing practice, the quality of patient care, and the patient’s health outcome.
Firouzeh Safavi   +4 more
doaj   +1 more source

Faculty and student perspectives on the teaching of nontraditional accounting students [PDF]

open access: yes, 2003
The study explores two research questions: Q1, What teaching methods do four-year accounting faculty use with nontraditional accounting students; and Q2, how effective do accounting faculty and students perceive those methods to be with nontraditional ...
Jinkens, Robert Carl
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The Ten Principles of the Bologna Process and Credit Modelin the Postgraduate Education in the Peoples' Friendship University of Russia

open access: yesVestnik RUDN. International Relations, 2008
The innovative approach to the development of the postgraduate education in Russia means system changes in format and content of the educational process as itself.
O V Andreeva
doaj  

Development and Application of an AI-based Empathic Language Teaching and Evaluation System for Doctor-patient Communication [PDF]

open access: yesZhongguo quanke yixue
Background Under the background of new medical science, the deep integration of information technology and medical education is encouraged to train first-class medical talents to serve the construction of healthy China.Currently, empathy training in ...
SHAO Jianwen, LIU Huan, ZHANG Yue, ZHENG Aiming, CHEN Songyu, WANG Jinfan
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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