Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
A randomized controlled trial of a WeChat-based artificial intelligence agent for postoperative care in orthopedic patients. [PDF]
Li J +6 more
europepmc +1 more source
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
The impact of acupuncturists' experience level on the efficacy of acupuncture for functional dyspepsia: an exploratory secondary analysis of a randomized clinical trial. [PDF]
Jiang J +13 more
europepmc +1 more source
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
Memory and thinking problems that aging Latinos in New York City would bring to a doctor's attention. [PDF]
Siegel K +5 more
europepmc +1 more source
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Does Family Doctor Contracting Improve the Health of the Elderly: An Empirical Study from Beijing, China. [PDF]
Lv B, Wang Z, Meng K.
europepmc +1 more source
Patient Preferences for Cancer Care Within Hub-and-Spoke Networks: A Discrete Choice Experiment. [PDF]
Broman KK +4 more
europepmc +1 more source
Why has continuity of general practitioner care been neglected? [PDF]
Pereira Gray D +3 more
europepmc +1 more source

