Results 51 to 60 of about 1,611,625 (301)

Digital Leadership and Innovation in Indonesia’s Public Administration: Insights from the Govtech INA Digital Reform

International Journal of Social Science and Religion
This study explores how digital leadership influences innovation in Indonesia’s public sector amid the nationwide implementation of GovTech INA Digital and the updated Electronic Based Government System (SPBE).
Ariawan, Triyuni Soemartono, Khasan Effendy, Pandji Sukmana   +3 more
doaj   +1 more source

International mobility and doctorate holders' career: Some evidence from Spain [PDF]

, 2017
The completion of the PhD program is understood as a transmission channel to provide high specialization and skills to students pursuing to be employed as highly-qualified workers or researchers.
Caparros-Ruiz, Antonio
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Policy Diffusion, Digitalisation, and Governance Gaps in the Implementation of Indonesia's Golden Visa Programme

Journal of Global Strategic Studies
Indonesia’s Golden Visa, launched in 2023 through Minister of Law and Human Rights Regulation No. 22/2023, is promoted as a residence-by-investment scheme to attract foreign capital and talent for post-pandemic recovery and digital transformation.
Gunawan Ari Nursanto, Sunarto Sunarto, Pandji Sukmana, Gatot Hery Djatmiko   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Digitalisation of Border Control through Autogate and the Emerging Configuration of Immigration System Resilience in Indonesia

International Journal of Social Science and Religion
This article examines Indonesia’s autogate policy not only as a digital service innovation, but as a component of immigration system resilience. Drawing on policy implementation theory by Edwards III, Sabatier & Mazmanian, e-government literature on the
Besse Hartati, Sunarto, Pandji Sukmana, T. Herry Rachmatsyah   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

CO-CREATION AND THE CREATIVE ECONOMY : REDEFINING PUBLIC SERVICE DELIVERY FOR INCLUSIVE INNOVATION

Journal of Management Small and Medium Enterprises (SME's)
The creative economy has emerged as a dynamic engine of economic resilience and social innovation, especially in the aftermath of the COVID-19 pandemic.
Dessy Ruhati, Triyuni Soemartono, Khasan Effendy, T. Herry Rachmatsyah   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

What Engages Doctoral Students in Biosciences in Doctoral Studies?

Psychology, 2012
Reduced levels of engagement and dropping out have been identified as a major problem in doctoral education worldwide, including in the biosciences. Research suggests that engagement predict student satisfaction, degree completion, and persistence in studies.
Viivi Virtanen, Kirsi Pyhalto
openaire   +2 more sources