Results 231 to 240 of about 398,438 (271)

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

How Are Pedagogical Practices Within Medical Education Being Adapted for Autistic Students? [PDF]

Cureus
Harker A, Tarafdar S.
europepmc   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Research self-efficacy in early-career pharmacists: Tool validation and correlation with personal attributes. [PDF]

Explor Res Clin Soc Pharm
Hajj A, Sacre H, Haddad C, Elia J, El Ghawi J, Haidar L, Dimachkieh L, Nasrallah M, Safwan J, Rahme D, Basma S, Pascale S.   +11 more
europepmc   +1 more source

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics

Advanced Science, EarlyView.
Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu, Yu Wang, Haibo Zhou, Mingen Li, Yang Wang, Lingwei Wang, Hui Mei, Junbiao Dai, Shanze Chen, Xiaoluo Huang   +9 more
wiley   +1 more source

Academic generational differences in Chinese universities: Work preferences, research behaviors and research outputs. [PDF]

PLoS One
Cui Y, Guo H.
europepmc   +1 more source

Cardiac atrophy associated to cancer: new perspectives in signaling pathways. [PDF]

Mol Biomed
Lodeiro AC, Leal-López S, Costas-Abalde S, Debasa-Corral L, Otero-Fraga MJ, Vilar J, Ait-Oufella H, Pazos Y, Camiña JP, Santos-Zas I.   +9 more
europepmc   +1 more source

Contraceptive methods: Knowledge and factors influencing their choice among women of reproductive age-A cross-sectional study in Portugal. [PDF]

Aten Primaria
Rua S, Cardoso C, Silva I.
europepmc   +1 more source

Vaccine hesitation: attitudes of Turkish health worker parents towards adult and childhood immunisation. [PDF]

BMC Public Health
Çelik E, Şahin ÇE, Değer MS, Altaş ZM.   +3 more
europepmc   +1 more source