Results 51 to 60 of about 398,438 (271)
, 2004 [Excerpt] John Windmuller received his doctorate in industrial and labor relations from Cornell in 1951-one of the first granted by the school-the same year he was appointed to the ILR School faculty. In 1983 he was named the Martin P.
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
GMS Zeitschrift für Medizinische Ausbildung, 2010 [english] Objective: The integration of scientific research into medical education is a widely discussed topic. Most research training programs are offered on a voluntary basis.
Kuhnigk, Olaf +7 more
doaj +1 more source
International mobility and doctorate holders' career: Some evidence from Spain [PDF]
, 2017 The completion of the PhD program is understood as a transmission channel to provide high specialization and skills to students pursuing to be employed as highly-qualified workers or researchers.
Caparros-Ruiz, Antonio
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Examining academic vs. applied doctorate [PDF]
, 2015 The role of formal education in general and of university education in particular is often discussed nowadays. We have engaged in this debate previously, arguing that although it is bound to change, university education is here to stay. We have developed
Baracskai, Zoltán +3 more
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
WITHDRAWAL OF THE DOCTORAL TITLE [PDF]
Challenges of the Knowledge SocietyIn modern society, where the emphasis is on knowledge, development and innovation, university doctoral studies, whose inestimable value for scientific progress is universally recognized, constitute the means of creation and the symbol of intellectual ...
Dana Maria IOAN
doaj