Results 111 to 120 of about 1,115,615 (333)
Advanced Science, EarlyView.RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan +9 more
wiley +1 more source
Advanced Science, EarlyView.A CoCrFeNiTa0.4 eutectic high‐entropy alloy achieves a near‐theoretical yield strength of 2.6 GPa with 13.6% plasticity. This breakthrough stems from a hierarchical nanostructure (FCC‐Laves lamellae with L12/D022 precipitates), which alleviates the inter‐phase modulus/hardness mismatch through synergistic strengthening and toughening, guiding the ...
Yusha Luo +10 more
wiley +1 more source
The Quest for the Causal Joint [PDF]
, 2012 This study is an examination of three proposals for a \"causal joint\" model of God\'s action in the world. Adapting the thought of Austin Farrer and David Burrell, the author seeks to show how these hypotheses are theologically flawed.
Doran, Chris
core +1 more source
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
Advanced Science, EarlyView.This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
Advanced Science, EarlyView.A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source
Advanced Science, EarlyView.Super‐stretchable and self‐healing polyacrylate ternary ionogel elastomers are used for flexible i‐TE devices. Based on Gutmann donor theory of doped anion, the work proposes a three‐parameter tuning strategy of flexible polymer‐doped anion‐synergistic cation to achieve the systematic design of ionic thermoelectric materials. Abstract Quasi‐solid‐state,
Bin Chen +9 more
wiley +1 more source
The National Security Consequences of the Major Questions Doctrine
, 2023 Timothy Meyer, Ganesh Sitaraman
openalex +2 more sources
Advanced Science, EarlyView.A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo +8 more
wiley +1 more source