Results 91 to 100 of about 15,114 (254)

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Sistemi upravljanja sadržajem - pojam i karakteristike / Content management systems: Concept and features

Vojnotehnički Glasnik, 2010
Rad predstavlja kratak prikaz osnova programskog rešenja koje je u poslednjih desetak godina okupiralo sve veće i ozbiljne poslovne organizacije koje svoje poslovanje, celokupno ili delimično, zasnivaju na principima Internet tehnologija i elektronskog ...
Dejan S. Milenković, Marina V. Jovanović-Milenković, Zoran A. Radojičić   +2 more
doaj   +1 more source

A Symmetric Cogeneration Fuel Cell for Coupled Production of Hydrogen, Ammonia and Formate

Advanced Science, EarlyView.
A symmetric cogeneration fuel cell integrating value‐added chemical synthesis with electricity generation by coupling formaldehyde oxidation with the nitrate reduction was developed. This work highlights the broader potential of symmetric cogeneration fuel cells as a general platform for rational reaction pairing, offering a practical pathway to lower ...
Yingjie Song, Peimiao Zou, Renhang Wang, Qi Zhang, Yisong Han, Christopher Waldron, Marc Walker, Ben G. Breeze, Shanwen Tao   +8 more
wiley   +1 more source

A comparison study of NoSQL document-oriented database system

International Journal of Applied Mathematical Research, 2019
By increasing data generation at these day, requirement for a sufficient storage system are strongly needed by stakeholders to store and access huge number of data in efficient way for fast analysis and decision. While RDBMS cannot deal with this challenge, NoSQL has emerged as a solution to address this challenge.
Sugimiyanto Suma, Fahad Alqurashi
openaire   +2 more sources

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

Natural-language interfaces to a process-aware, graph-based ELN: An UV coatings case study

Digital Chemical Engineering
This work introduces a process-aware data management framework for formulation research built upon a graph-database architecture. In contrast to conventional electronic laboratory notebooks that rely on relational or document-oriented data structures ...
Gaoyuan Zhang, Christoph Quix, Sayed Hoseini, Christian Schmitz   +3 more
doaj   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source

How firearm legislation impacts firearm mortality internationally: A scoping review

Health Policy Open
Background: The literature on gun violence is broad and variable, describing multiple legislation types and outcomes in observational studies. Our objective was to document the extent and nature of evidence on the impact of firearm legislation on ...
Brianna Greenberg, Alexandria Bennett, Asad Naveed, Raluca Petrut, Sabrina M. Wang, Niyati Vyas, Amir Bachari, Shawn Khan, Tea Christine Sue, Nicole Dryburgh, Faris Almoli, Becky Skidmore, Nicole Shaver, Evan Chung Bui, Melissa Brouwers, David Moher, Julian Little, Julie Maggi, Najma Ahmed   +18 more
doaj   +1 more source

A scalable transaction management framework for consistent document-oriented NoSQL databases

Information Systems
NoSQL databases are widely used in modern applications due to their scalability and schema flexibility, yet they often rely on eventual consistency models that limit reliable transaction processing. This study proposes a four-stage transaction management framework for document-oriented NoSQL databases, with MongoDB as the reference platform.
Adam A. E. Alflahi, Mohammed A. Y. Mohammed, Abdallah Alsammani   +2 more
openaire   +2 more sources