Results 111 to 120 of about 3,531,886 (311)

Evaluation of a Prototype Interface for Structured Document Retrieval

open access: yes, 2003
Document collections often display either internal structure, in the form of the logical arrangement of document components, or external structure, in the form of links between documents.
Dunlop, M.D., Reid, J.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

L’art face au livre

open access: yesAppareil
The article analyzes the various ways of articulating together the four concepts of the debate: the book, the medium, the text, and the work of art. Schematically, this encounter through the book object outlines three distinct regions : where the book ...
Pascal Krajewski
doaj   +1 more source

Electronic publishing and document delivery

open access: yes, 1985
SIGLEAvailable from British Library Document Supply Centre- DSC:2113.56F(BLRDR--5866) / BLDSC - British Library Document Supply CentreGBUnited ...
British Library, London (United Kingdom). Research and Development Dept
core  

Document-Level Neural Machine Translation With Document Embeddings

open access: yes
Standard neural machine translation (NMT) assumes that document-level context information is irrespective. Most existing document-level NMT methods are satisfied with a smattering sense of shallow document-level information, such as using a few context ...
Jiashuang Huang   +6 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Razón moral, razón política, razón ficcional: en torno a El monarca de las sombras (2017) de Javier Cercas y la ficción de archivo

open access: yesCuadernos LIRICO
The novel by Spanish writer Javier Cercas, The Monarch of Shadows (2017), closes a cycle of archival fiction inaugurated by his most famous work, Soldiers of Salamis (2001).
Yael Natalia Tejero Yosovitch
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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