Results 111 to 120 of about 5,189,134 (308)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Identification of Computer Editing in Electronic Images of Documents as a Task of Forensic Examination

open access: yesТеория и практика судебной экспертизы
The article considers a number of theoretical and applied issues related to forensic examination of electronic images of documents and in particular:- comparative analysis of normative legal acts carried out with regard to regulation of certain aspects ...
A. F. Kupin, A. S. Kovalenko
doaj   +1 more source

Examination papers for the academic year ... /

open access: yes, 1893
Description based on: 1891-92, 2nd edition.Mode of access ...
University of the State of New York. Examination Dept.
core  

Forensic intelligence: Expanding the potential of forensic document examination [PDF]

open access: yes
Forensic document examination is characterized by its longevity, diversity, and evolution over time. Predominantly, published research within this field has focused on handwriting examination, the articulation of forensic conclusions, and the development
Devlin, Ciara   +5 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Digital and document examination

open access: yes, 2018
The Advanced Forensic Science Series grew out of the recommendations from the 2009 NAS Report: Strengthening Forensic Science: A Path Forward. This volume, Digital and Document Examination, will serve as a graduate level text for those studying and ...
Houck, Max M.
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Exploratory Quantitative Assessment of Signature Variability Related to Shift Duration Using the Signature Change Scale

open access: yesApplied Sciences
Handwritten signatures retain their legal validity and play a central role in the forensic examination of documents. While it is recognized that signatures can be influenced by contextual and human factors, research on the systematic evaluation of ...
Samet Kıyak   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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