Results 81 to 90 of about 35,378,370 (305)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A statistical learning approach to document image analysis [PDF]

Eighth International Conference on Document Analysis and Recognition (ICDAR'05), 2005
In the field of computer analysis of document images, the problems of physical and logical layout analysis have been approached through a variety of heuristic, rule-based, and grammar-based techniques. In this paper we investigate the effectiveness of statistical pattern recognition algorithms for solving these two problems, and report results ...
Kevin Laven, Scott Leishman, Sam T. Roweis   +2 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

"Quality" vs. "Readability" in Document Images: Statistical Analysis of Human Perception

, 2018
International audienceBased on the hypothesis that a good / poor quality document image is most probably a readable / unreadable document, document image quality and readability have interchangeably been used in the literature.
Raveaux, Romain, Stantic, Bela, Alaei, Ali Reza, Alaei, Alireza, Conte, Donatello   +4 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Segmentation of Thai handwritten text for automatic document retrieval [PDF]

, 2008
There is a huge amount of documents in Thai government organizations. Although automatic document image retrieval systems in English have been proposed and developed, there are no specific system which is capable to retrieve relevant information from ...
Fung, C.C., Chamchong, R.
core  

Document expansion for text-based image retrieval at WikipediaMM 2010 [PDF]

, 2010
We describe and analyze our participation in the Wikipedi- aMM task at ImageCLEF 2010. Our approach is based on text-based image retrieval using information retrieval techniques on the metadata documents of the images.
Min, Jinming, Leveling, Johannes, Jones, Gareth J.F.   +2 more
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Hybrid Object Detection and Semantic Segmentation for Offline Handwritten Diagram Understanding

IEEE Access
This work addresses the problem of offline handwritten diagram understanding by proposing a hybrid framework that integrates object detection, semantic segmentation, and optical character recognition (OCR) to reconstruct the complete topological ...
Daniela De Sousa Costa, Carlos Alexandre Barros De Mello   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source