Results 81 to 90 of about 35,694,464 (306)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Old document image segmentation using the autocorrelation function and multiresolution analysis

, 2013
International audienceRecent progress in the digitization of heterogeneous collections of ancient documents has rekindled new challenges in information retrieval in digital libraries and document layout analysis.
Maroua Mehri, Rémy Mullot, Mullot, Rémy, Mehri, Maroua, Pierre Héroux, Gomez-Krämer, Petra, Petra Gomez-Krämer, Héroux, Pierre   +7 more
core   +1 more source

Image analysis in technical documentation

, 2019
In the era of Big Data, manufacturing companies are overwhelmed by a lot of disorganized information: the large amount of digital content that is increasingly available in the manufacturing process makes the retrieval of accurate information a critical issue.
Carrara F, Debole F, Gennaro C, Amato G
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Human Interactive Proofs and Document Image Analysis [PDF]

, 2002
The recently initiated and rapidly developing research field of 'human interactive proofs' (HIPs) and its implications for the document image analysis (DIA) research field are described. Over the last five years, efforts to defend Web services against abuse by programs ('bots') have led to a new family of security protocols able to distinguish between ...
Henry S. Baird, Kris Popat
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Benchmark Study of Classical and U-Net ResNet34 Methods for Binarization of Balinese Palm Leaf Manuscripts

Heritage
Ancient documents that have undergone physical and visual degradation pose significant challenges in the digital recognition and preservation of information.
Imam Yuadi, Khoirun Nisa’, Nisak Ummi Nazikhah, Yunus Abdul Halim, A. Taufiq Asyhari, Chih-Chien Hu   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Breast cancer histopathology image analysis : a review

, 2014
This paper presents an overview of methods that have been proposed for the analysis of breast cancer histopathology images. This research area has become particularly relevant with the advent of whole slide imaging (WSI) scanners, which can perform cost ...
Pluim, J.P.W., Veta, M., Diest, van, P.J., Viergever, M.A.   +3 more
core   +1 more source