Results 71 to 80 of about 143,752 (266)

Feature Approach for Printed Document Image Analysis [PDF]

open access: yes, 2002
This paper presents advances in zone classification for printed document image analysis. It firstly introduces entropic heuristic for text separation problem. Then a brief recall on existing texture and geometric discriminant parameters proposed in a previous research is done.
Jean Duong, Myriam Côté, Hubert Emptoz
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A Printed PAW Image Database of Arabic Language for Document Analysis and Recognition

open access: yesJournal of ICT Research and Applications, 2017
Document image analysis and recognition are important topics in the field of artificial intelligence. In this context, the availability of a database with good script samples is an important requirement for machine-learning processes. For Latin and Asian
Bilal Bataineh
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

A Deep Learning-Based Approach for Part of Speech (PoS) Tagging in the Pashto Language

open access: yesIEEE Access
A fundamental task in natural language processing (NLP) is part of speech (PoS) tagging. PoS tagging is crucial to many NLP applications, including question answering, machine translation, syntactic parsing, speech recognition, and semantic parsing.
Shaheen Ullah   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

PicAxe: Extracting Figures from Structurally and Syntactically Heterogeneous Corpora of PDF Files

open access: yesJournal of Open Research Software
PicAxe is open-source Python software that researchers can use to extract figures from corpora of PDF files that contain text and images. It is designed to extract figures from corpora that include both scanned and “born-digital” PDF files (structurally ...
Anna C. Guerrero   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

From Sketch to Structure: Agentic Prompting for Business Process Diagram Understanding With Vision–Language Models

open access: yesIEEE Access
Converting real-world process diagrams into structured, executable representations remains challenging: systems must detect heterogeneous symbols, read noisy text, and reconstruct flow topology.
Pritam Deka, Barry Devereux
doaj   +1 more source

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