Results 41 to 50 of about 64,341 (260)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
An enhanced binarization framework for degraded historical document images
Binarization plays an important role in document analysis and recognition (DAR) systems. In this paper, we present our winning algorithm in ICFHR 2018 competition on handwritten document image binarization (H-DIBCO 2018), which is based on background ...
Wei Xiong +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Deep Learning Method for Handwriting Recognition
The advancement of technology nowadays resulted into documents, such as forms and petitions, being filled out in computer and digital environment. Yet in some cases, documents are still preserved in traditional style, on print.
Abdullah Erdal Tümer +1 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Comparative Semantic Document Layout Analysis for Enhanced Document Image Retrieval
Tons of handwritten document images, either historical or continuously reproduced in everyday life, are information-rich, awaiting extensive advanced technological attention from academic and industrial communities.
Emad Sami Jaha
doaj +1 more source
Intelligent classification on images of Dongba ancient books
Dongba hieroglyphs are the only living hieroglyphs in the world today and are still used by people. The various ritual activities in Dongba culture are passed down through the Dongba hieroglyphs in the form of books. In view of the current classification
Ruxiang Hua, Xiaoli Xu
doaj +1 more source
Automated classification of satellite images is a challenging task that enables the use of remote sensing data for environmental modeling of Earth’s landscapes.
Polina Lemenkova
doaj +1 more source

