Results 91 to 100 of about 28,159,374 (267)
Investigation of Electronic Document Management System Usability across User Groups
Applied Computer SystemsThe growing reliance on Electronic Document Management Systems (EDMSs) in public institutions necessitates an improved understanding of usability across diverse user groups.
Aksu Muhammed Çağrı, Alan Alper Turan
doaj +1 more source
Developing a risk management "flight simulator" for manned space programs : a user interface to a system dynamic simulation of system safety at NASA [PDF]
, 2006 Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, February 2006.Includes bibliographical references (p. 81-82).Simulators are a staple of any engineering project and manned space flight in particular.
Friedenthal, Stephen R. (Stephen Roger)
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Supporting Tangible User Interaction with Integrated Paper and Electronic Document Management Systems [PDF]
, 2011 Although electronic technology has had a significant impact on the way that offices manage documents, in most cases electronic documents have not completely replaced paper documents.
Jervis, Matthew Geoffrey
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
System level variation analysis of product development
, 2002 Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2002.Includes bibliographical references (leaf 87).by Charles M.
Hura, Charles M. (Charles Michael), 1961-
core
Power management as a system-level inhibitor of modularity in the mobile computer industry [PDF]
, 2004 Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2004.Includes bibliographical references (p. 88-90).Since the mid-90s, the computer industry has been very modular with respect to both product architecture and ...
Weinstein, Samuel K. (Samuel Keith), 1974-
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source