Objectives Evaluate the efficacy and safety of baricitinib in paediatric patients with active JIA‐U or chronic anterior ANA‐positive uveitis, who had an inadequate response to MTX or bDMARDs. Methods JUVE‐BRIGHT was an open‐label, active‐controlled, Phase‐3 multicentre trial which utilized a novel design, including 1:1 randomization to an active ...
Athimalaipet V. Ramanan+7 more
wiley +1 more source
Design of a Sensor-Based Digital Product Passport for Low-Tech Manufacturing: Traceability and Environmental Monitoring in Bio-Block Production. [PDF]
Pracucci A, Giovanardi M.
europepmc +1 more source
Document Management Systems in Higher Education
Nikolett Fanni Menyhart+2 more
openaire +1 more source
Objectives The objectives of this study were to evaluate the correlation and agreement between ultrasound and computed tomography (CT) in measuring ascending aorta diameter in patients with giant cell arteritis (GCA) and to investigate the development of new ascending aortic aneurysms in patients with newly diagnosed GCA. Methods To achieve the primary
Anne C Bull Haaversen+4 more
wiley +1 more source
Critical analysis of the liver cancer policies and programs in China: implications for international liver cancer control. [PDF]
Chen X+6 more
europepmc +1 more source
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán+10 more
wiley +1 more source
Centralized daily drug management in clinical trial institutions and specific implementation plans. [PDF]
Tang Y, Fang X.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Rancang Bangun Document Management System Untuk Mengelola Dokumen Standart Operational Procedure
I Putu Susila Handika+1 more
doaj +1 more source
From policy to action: a document content analysis reviewing the adoption of the healthcare inequalities programme in local health system plans in England. [PDF]
Elliott H+7 more
europepmc +1 more source