Results 151 to 160 of about 201,449 (246)

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Illuminating New Frontiers: Exploring the Photosensitizing Potential of Passiflora Species in Combating Methicillin‐Resistant Staphylococcus aureus (MRSA) and Their Infection in Senescent Mice

open access: yesAdvanced Biology, EarlyView.
This study investigates the photosensitizing potential of Passiflora cincinnata in Antimicrobial Photodynamic Therapy (aPDT) against skin infection caused by Methicillin‐resistant Staphylococcus aureus (MRSA) in a senescent murine model. The P. cincinnata exhibits antimicrobial activity, with reduced bacterial load, lower leukocyte infiltration, and ...
Caroline Vieira Gonçalves   +14 more
wiley   +1 more source

Tracking a Medicine's Regulatory Risk Management Commitments Provides Better Transparency and Oversight. [PDF]

open access: yesTher Innov Regul Sci
Ingate S   +5 more
europepmc   +1 more source

Mechanical Behavior and Microstructural Changes Associated with Tensile Deformation above the Martensite Start Temperature during Quenching and Subsequent Partitioning of a Low‐Alloy 37SiB6 Steel

open access: yesAdvanced Engineering Materials, EarlyView.
A new experimental setup, incorporating digital image correlation and infrared thermography in combination with inductive‐conductive heating for precise temperature control, is used to analyze the mechanical behavior and microstructural changes of sheet metal under complex thermomechanical test conditions that represent quench and partitioning ...
Christian Illgen   +4 more
wiley   +1 more source

Laboratory‐Scale Procedure for Evaluating the Flux Efficiency on Melt Cleanliness and Tensile Properties of Recycled Aluminum Alloys

open access: yesAdvanced Engineering Materials, EarlyView.
A laboratory‐scale procedure is developed to evaluate the efficiency of melt‐cleaning and drossing fluxes during aluminium alloy recycling, studying their effects on melt cleanliness and tensile properties of secondary foundry alloys. This work provides a practical tool for foundries and aluminium refiners to assess the efficiency of salt fluxes in ...
Veronica Milani, Giulio Timelli
wiley   +1 more source

(Nb,Ti)(C,N)‐Precipitates in High‐Strength Low‐Alloyed Steels—Modeling, Characterization and Validation

open access: yesAdvanced Engineering Materials, EarlyView.
Steel samples are investigated using complementary simulations and measurements. Transmission electron microscopy in bright‐field mode, combined with energy‐dispersive X‐ray spectroscopy maps for titanium and niobium, reveals distinct particle populations. Simulations reproduce these in size and composition.
Marc Laub   +3 more
wiley   +1 more source

Soft Beats: A Dielectric Elastomer‐Based Ventricular Assist Device for Next‐Gen Heart Failure Management

open access: yesAdvanced Engineering Materials, EarlyView.
The dielectric elastomer‐based electropneumatic device (DE‐EPD) is a vacuum‐assisted ventricular assist device (VAD) that delivers high performance (85 mmHg, 6.8 L min−1) with low power consumption. Unlike traditional motor‐driven VADs, it is lightweight, quiet, energy‐efficient, and provides pulsatile flow. Validated in a simulated circulation system,
Amine Benouhiba   +6 more
wiley   +1 more source

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