Results 41 to 50 of about 275,231 (310)

Creating a maturity model for a document management system [PDF]

, 2021
The purpose of this study was to find how maturity models could be used to evaluate the current state of a document management system, in use in order to better understand custom-er’s situation and ways to improve their satisfaction.
Simolin, Klaus
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and Evaluation of a Low-Code/No-Code Document Management and Approval System

Information
This paper presents the design, implementation, and evaluation of a low-code document management and approval system developed on the Microsoft Power Platform.
Constantin Viorel Marian, Mihnea Neferu, Dan Alexandru Mitrea   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

NILDE: developing a new generation tool for document delivery [PDF]

, 2007
This paper presents the most recent progress and implementation of the NILDE (Network Inter-Library Document Exchange) system, which was developed by the National Research Council (CNR) Bologna Research Area Library.
De Matteis, Daniele, Tenaglia, Giacomo, Mangiaracina, Silvana, Beghelli, Enrico, Tugnoli, Alessandro, Zaetta, Marta   +5 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

DOMAIN INDEPENDENT SERVER FOR DOCUMENT MANAGEMENT SYSTEM

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Domain independent server for document management system is detailed. Server plays a role of basic software which allows to extend functionality of the system. Main objective of suggested server is processing requests from representation layer.
M. V. Sterjanov, I. V. Baidakov
doaj  

Role of document management system for business processes optimization

Проблеми теорії та методології бухгалтерського обліку, контролю і аналізу
The automation of work processes and seamless integration with various business services highlight the essential role of digital document management systems (DMS) in enhancing organizational flexibility, productivity, and adaptability.
I.V. Orlov
doaj   +1 more source