Results 51 to 60 of about 196,499 (309)
Bilişim teknolojileri birçok alanda olduğu gibi kamu hizmetlerinin yapılandırılmasında ve vatandaş devlet ilişkilerinde de çeşitli değişimlere yol açmıştır.
Şahika Eroğlu, Özgür Külcü
doaj +1 more source
Naval Air Systems Command (NAVAIR) is moving from traditional Systems Engineering (SE), focusing on managing documentation, to Model Based Systems Engineering (MBSE), focusing on a system model (All Partners Access Network, n.d.).
David R Zubowski
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Document Management and Work Flow Systems on the Way to E- Transformation
Document Management Systems covering all the document and information flow in an enterprise are built to decrease the costs and increase the productivity in the document related operations such as creating, controlling, preserving, accessing and ...
A.Eser Baransel, İlker Tabak
doaj
Healthcare systems operating under emergency and high-demand conditions face persistent challenges in coordinating medical personnel, managing critical documentation, and ensuring data security and regulatory compliance.
Azir Aliu, Rexhep Mustafovski
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Information security in electronic document management systems [PDF]
Мета статті полягає у виявленні загроз інформаційної безпеки систем електронного документообігу, які використовуються в державних та комерційних структурах, на великих та середніх підприємствах, в організаціях, установах, і шляхів їх подолання.
Pavlichenko, V. M. +3 more
core +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An integrated document management system
We propose an approach towards an integrated document processing and management system that has the intention to capture essentially freely structured documents, like those typically used in the office domain. The ANASTASIL component is capable to reveal the structure as well as the contents of complex office documents.
Dengel, Andreas +2 more
openaire +1 more source

