Results 51 to 60 of about 196,499 (309)

TS 13298 Çerçevesinde Kurumsal Bilgi Sistemleri ve Elektronik Belge Yönetimi Standartlarının Değerlendirilmesi: İçişleri Bakanlığı Örneği=The Evaluation of Enterprise Information Systems and Electronic Records Management Standards within the scope of TS 13298: A Case of the Ministry of Internal Affairs

open access: yesBilgi Dünyası, 2014
Bilişim teknolojileri birçok alanda olduğu gibi kamu hizmetlerinin yapılandırılmasında ve vatandaş devlet ilişkilerinde de çeşitli değişimlere yol açmıştır.
Şahika Eroğlu, Özgür Külcü
doaj   +1 more source

Configuration Management Challenges of Model Based Systems Engineering on Multiple Variant Aircraft Fleets

open access: yesJournal of Aviation/Aerospace Education & Research, 2020
Naval Air Systems Command (NAVAIR) is moving from traditional Systems Engineering (SE), focusing on managing documentation, to Model Based Systems Engineering (MBSE), focusing on a system model (All Partners Access Network, n.d.).
David R Zubowski
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Document Management and Work Flow Systems on the Way to E- Transformation

open access: yesTürk Kütüphaneciliği, 2006
Document Management Systems covering all the document and information flow in an enterprise are built to decrease the costs and increase the productivity in the document related operations such as creating, controlling, preserving, accessing and ...
A.Eser Baransel, İlker Tabak
doaj  

A SECURE AND AUTOMATED DIGITAL FRAMEWORK FOR HEALTHCARE PERSONNEL AND DOCUMENT MANAGEMENT IN EMERGENCY AND HIGH-DEMAND CONDITIONS

open access: yesАвтоматизация технологических и бизнес-процессов
Healthcare systems operating under emergency and high-demand conditions face persistent challenges in coordinating medical personnel, managing critical documentation, and ensuring data security and regulatory compliance.
Azir Aliu, Rexhep Mustafovski
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Information security in electronic document management systems [PDF]

open access: yes, 2019
Мета статті полягає у виявленні загроз інформаційної безпеки систем електронного документообігу, які використовуються в державних та комерційних структурах, на великих та середніх підприємствах, в організаціях, установах, і шляхів їх подолання.
Pavlichenko, V. M.   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

An integrated document management system

open access: yes, 2015
We propose an approach towards an integrated document processing and management system that has the intention to capture essentially freely structured documents, like those typically used in the office domain. The ANASTASIL component is capable to reveal the structure as well as the contents of complex office documents.
Dengel, Andreas   +2 more
openaire   +1 more source

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