Results 91 to 100 of about 1,973,880 (305)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Validation Experiment on the Ordering Key DS and an Unified Syntax for the Weight DS [PDF]
, 1999 This document presents the experimental results for validating the Ordering Key DS (DS5) in the context of the core experiment of the Weight DS [6]. At the Melbourne MPEG meeting, in October 1999, the aforementioned core/validation experiment was planned
ADAMI N. +3 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Document Simplicial Complex [PDF]
, 2018 A k-simplex is de ned as k-dimensional geometric structure which is the convex hull of k+1 points. Given k+1 points x0; :::; xk 2 Rk which are a nely independent, the set C = ( a0x0 + ::: + akxk Xk i=0 ai = 1 and ai 0 for all i ) ; is ...
Kaul, Manohar, Mishra, Varun
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
RATFOR user's guide version 2.0 [PDF]
This document is a user's guide for RATFOR at Ames Research Center. The main part of the document is a general description of RATFOR, and the appendix is devoted to a machine specific implementation for the Cray X-MP.
Helmle, L. C.
core +1 more source
Analysis of Video Content for a Multi-Layer Navigation of Multimedia Documents [PDF]
, 1999 This paper describes a set of automatic extraction tools so as to generate a three-layer organization of video documents. The underlying coarse to fine description allows for a fast navigation throughout the document, depending on the degree of details ...
BONNET M. +3 more
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Investing in Knowledge: Insights on the Funding Landscape for Research on Inequality Among Young People in the United States [PDF]
, 2015 This report maps the current funding environment for research on understanding and addressing social and economic inequality among young people in the U.S.
Sarah K. Bruch
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