Results 121 to 130 of about 1,973,880 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A proposal for a world database on transport infrastructure regulation [PDF]

The paper presents the structure and the concepts at the basis of a database on world transport infrastructure regulation, to be launched. The database will be built promoting a “soft” survey on the world regulatory practices, to be filled by scholars ...
Beria, Paolo, Laurino, Antonio, Ponti, Marco   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Prevalence of osteoporosis in women wiht climacteric in a neighborhood of Esmeraldas city, Ecuador

Archivo Médico de Camagüey, 2020
Background: Informed Consent is the acceptance of a medical intervention by a patient, in a free, voluntary and conscious way, after the doctor has informed him of the nature of the intervention, risks, benefits and alternatives.
José Manuel De la Rosa-Ferrera, Hada Xiomara Cevallos-Rojas, Miren Barrado-Guezala   +2 more
doaj  

eROSITA Science Book: Mapping the Structure of the Energetic Universe

, 2012
eROSITA is the primary instrument on the Russian SRG mission. In the first four years of scientific operation after its launch, foreseen for 2014, it will perform a deep survey of the entire X-ray sky.
Becker, W., Boller, T., Brunner, H., Brusa, M., Böhringer, H., Dennerl, K., Freyberg, M., Friedrich, P., Georgakakis, A., Haberl, F., Hasinger, G., Hasinger, G., Meidinger, N., Merloni, A., Mohr, J., Nandra, K., Nandra, K., Predehl, P., Rau, A., Reiprich, T., Robrade, J., Salvato, M., Santangelo, A., Sasaki, M., Schwope, A., Wilms, J.   +25 more
core  

Extending the 5S Framework of Digital Libraries to support Complex Objects, Superimposed Information, and Content-Based Image Retrieval Services [PDF]

, 2010
Advanced services in digital libraries (DLs) have been developed and widely used to address the required capabilities of an assortment of systems as DLs expand into diverse application domains.
Archer, David, Delcambre, Lois, Fox, Edward, Goncalves, Marcos, Kozievitch, Nadia, Leidig, Jonathan, Murthy, Uma, Torres, Ricardo, Yang, Seungwon   +8 more
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Quality of written forms of informed consent in critically ill patients

Archivo Médico de Camagüey, 2020
Background: Informed Consent is the acceptance of a medical intervention by a patient, in a free, voluntary and conscious way, after the doctor has informed him of the nature of the intervention, risks, benefits and alternatives.
Anabel Hernández-Ruiz, Rebeca Iracema Delgado-Fernández, Carlos Omar Mitjans-Fuentes, Rosario González-Volta, Teresa Cuní-Rivera, Denis Díaz-González   +5 more
doaj  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source