Results 81 to 90 of about 1,973,880 (305)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

THE CENTRALIZED STRUCTURE OF FUND OF ASSESSMENT TOOLS OF EDUCATIONAL PROGRAM

Высшее образование в России, 2017
. The centralized structure of assessment tools of the main educational program of higher education consists of the following documents:- fund of assessment tools of the educational program — the central document uniting information on competences ...
Elena Yu. Shakhova, Elena V. Nester, Il’ya S. Sitov   +2 more
doaj  

FRBR and RDA: What They Are and How They May Affect the Future of Libraries

Theological Librarianship, 2012
"Functional Requirements for Bibliographic Records," a document issued by the International Federation of Library Association’s Cataloguing Section in 1997, has achieved the status of an important theoretical model of the cataloging process, in effect, a
Charles R. Croissant
doaj   +1 more source

The availability of reliable information about medicines in Serbia for health professionals summary of product characteristics [PDF]

Hospital Pharmacology, 2015
Introduction Today, there are many drugs for the treatment of a large number of indicator areas. Significant financial resources are invested in research with the aim of introducing reliable therapeutics to therapy.
Đukić Ljiljana C., Terzića Branka M.
doaj   +1 more source

Evidence of Intermittent Cascades from Discrete Hierarchical Dissipation in Turbulence

, 2001
We present the results of a search of log-periodic corrections to scaling in the moments of the energy dissipation rate in experiments at high Reynolds number (2500) of three-dimensional fully developed turbulence.
Anifrani, Anselmet, Bacry, Barenblatt, Benzi, Bonn, Chhabra, Chhabra, Delour, Didier Sornette, Dubrulle, Dubrulle, Erzan, Feigenbaum, Frisch, Halsey, Horne, Huang, Huang, Huang, Johansen, Johansen, Johansen, Johansen, Johansen, Johansen, Johansen, Kolmogorov, Kraichnan, L’vov, Meneveau, Meneveau, Novikov, Novikov, Pázmándi, Saleur, Saleur, Scargle, She, She, Smith, Sornette, Sornette, Sornette, Sornette, Stauffer, Tchéou, Wei-Xing Zhou, Wiseman   +48 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Exploiting Query Structure and Document Structure to Improve Document Retrieval Effectiveness [PDF]

, 2006
In this paper we present a systematic analysis of document retrieval using unstructured and structured queries within the score region algebra (SRA) structured retrieval framework.
Apers, P.M.G., Blok, H.E., Hiemstra, D., Mihajlovic, V.   +3 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source