Results 51 to 60 of about 14,830 (269)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A través de la respectiva pasantía, se plantea como principal objetivo la realización de una propuesta a través de la cual se pueda contar con una estructura documental de un sistema de gestión de la calidad (Sistema el cual no se encuentra implementado ...
Ipus Leguizamón, Kevin Esteban +1 more
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THE PRIVATE CONSULTANCY IN EDUCATION MANAGEMENT AT CAMPINAS EDUCATION PUBLIC SYSTEM
This article aims at contributing to the comprehension of current managerial reforms that reconfigure the public administration. Within the agreement signed in 2013 between the Municipality of Campinas and Comunitas organization, we analyze specifically ...
Sara Badra de Oliveira
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Invest to Save: Report and Recommendations of the NSF-DELOS Working Group on Digital Archiving and Preservation [PDF]
Digital archiving and preservation are important areas for research and development, but there is no agreed upon set of priorities or coherent plan for research in this area.
Hedstrom, M. +9 more
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Duties and Required Competencies of a Management Contractor
One of the responses to the critical failings of separation of design and construction processes of traditional procurement system is the development of management contracting (MC) procurement system.
Calistus Ayegba
doaj +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Herramientas de software libre para la gestión de contenidos = Open source tools for content management [PDF]
Information and documentation services available on the Internet through web servers are growing in an exponential manner. The logical evolution of the Internet over the last 10 years has been producing a replacement of static web pages and documents by ...
Tramullas, Jesús +2 more
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