Results 81 to 90 of about 24,382,597 (254)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Percepciones de la alta gerencia y modelo de gestión por competencias en empresas de Bogotá

open access: yesSuma de Negocios, 2013
This article discusses the perceptions and competence management model from top management in companies of Bogotá. The paper includes two experiences, developed in the framework of the professional specialization in Human Resources Management at Konrad ...
Marleny Cardona Acevedo   +2 more
doaj  

Strengthening urban waste governance: Integrating data and policy in the northern coast of Rio Grande do Sul, Brazil

open access: yesAnais da Academia Brasileira de Ciências
Inadequate infrastructure for the final disposal of solid waste increases the vulnerability of coastal areas to environmental impacts. Poor waste management in these regions leads to severe marine contamination, as land-based waste reaches the oceans ...
MARÍLIA CERCINÁ   +3 more
doaj   +1 more source

The Perception of the Internal Managerial Control System – the Case of the Romanian Public Entities [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
In order to control the management of activities for achieve the objectives, the managers at all levels of the hierarchy must have relevant information on the organization's events and activities, in an appropriate form and detail.
State Violeta   +2 more
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Documentary production in Australia: a collection of key data [PDF]

open access: yes, 2008
Summary HOURS PRODUCED AND PRODUCTION BUDGETS Documentary production in Australia is estimated at around 296 hours (326 commercial broadcast hours), with production costs of $62 million a year. It makes up 3 per cent of total audiovisual production in

core  

Analysis of the Planning and Management of the Food Supply and Wholesale Distribution System in Barcelona and its Metropolitan Area (1971-2008)

open access: yesCuadernos de Geografía: Revista Colombiana de Geografía, 2011
The article identifies and assesses the planning and management of the food supply and wholesale distribution system in Barcelona, as well as the factors that have allowed for its growth and consolidation as one of the most important wholesale food ...
Maria del Pilar Leal Londoño
doaj  

Determinants of Credit Risk in Multiple Banking Institutions in Bolivia: A Systematic Review Using Prisma

open access: yesRevista Economía y Política
Risk management, with a particular focus on credit risk, is a fundamental element within the core activities of the financial system. Conducting an in-depth analysis of this aspect is essential for proper administration and informed decision-making. The
José Ramiro Villegas Mendoza   +1 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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