Results 221 to 230 of about 5,207,695 (291)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Food Safety Legislation, Standards, and Measures in Ethiopia: A Scoping Review. [PDF]

Environ Health Insights
Birara A, Motbainor A.
europepmc   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Temporal Annotation of German Clinical Language in Real and Synthetic Clinical Documents: Corpus Development and Baseline Tagger Validation Study.

J Med Internet Res
Modersohn L, Hahn U.
europepmc   +1 more source

The Communication Issue in Developing Childcare Services for Children Under Three Years of Age in China: An Analysis of Policy Texts and Practical Cases. [PDF]

Healthcare (Basel)
Liu H, Liu J.
europepmc   +1 more source

Is behaviour change communication guidance for general practice healthcare professionals evidence based? A systematic review. [PDF]

BMC Med
Schwarze-Chintapatla A, Livingstone-Banks J, Chua J, Albury C.   +3 more
europepmc   +1 more source

Eye movement and reading behavior in older adults with dementia. [PDF]

BMC Geriatr
Inuyama A, Ouchi M, Hirano S, Suwa S.
europepmc   +1 more source

Mapping weight stigma in food-based dietary guidelines across thirteen countries in Latin America and the Caribbean: a qualitative analysis. [PDF]

Lancet Reg Health Am
Lopez-Arana S, Aguilar Encina MF, Giovanetti VA, Basfi-Fer K, Tiscornia C, Estremadoyro C, Pereyra-González I.   +6 more
europepmc   +1 more source

Exploiting topic analysis models to explore psychological dimensions in social media data. [PDF]

Sci Rep
Couto M, Parapar J, Losada DE.
europepmc   +1 more source